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Background <p>As a leading cause of disability, chronic low back pain (CLBP) is a musculoskeletal condition often associated with impaired physical and cognitive functions. Due to its multi-factorial facets, the application of multimodal interventions is recommended. MultiMove is a multimodal intervention designed for CLBP patients, which combines motor-cognitive and dancing exercises. This study aimed to assess the effects of an additional MultiMove intervention to a standard inpatient rehabilitation on clinical and functional outcomes in CLBP patients.</p> Methods <p>For this prospective, two-arm, controlled pilot trial, 27 CLBP patients (17 females, 10 males) undergoing a 3-week inpatient rehabilitation, in a rehabilitation clinic in Germany, were recruited. The intervention group (IG, <i>n</i> = 15, 61.6 ± 1.8 years) received a daily MultiMove session in addition to the standard rehabilitation, while the control group (CG, <i>n</i> = 12, 63.8 ± 2.2 years) followed the standard rehabilitation. Physical (Timed Up and Go (TUG) [primary outcome], Five-Repetition Sit-to-Stand (FRSTS), and Six-Minute Walk Test (6MWT), trunk range of motion, single and dual task walking)), clinical (acute/chronic pain intensity, Oswestry Disability Index, EQ-5D-5&#xa0;L), cognitive (Stroop Color Word Test, Trail Making Test), and psychosocial outcomes (Tampa Scale of Kinesiophobia, Beck Depression Inventory-II, Coping Strategies Questionnaire) were assessed during the first (pre-test) and last day (post-test) of the inpatient rehabilitation.</p> Results <p>The statistical analyses revealed improvements in trunk range of motion (sagittal plane: <i>p</i> = 0.018, <i>d</i> = 1.00; transversal plane: <i>p</i> = 0.006, <i>d</i> = 1.18) and 6MWT performance (<i>p</i> = 0.003, <i>d</i> = 1.30) in the IG compared to the CG. Moreover, lower dual task costs for a gait variability measure (<i>p</i> = 0.034, <i>d</i> = 0.97) as well as reduced chronic pain intensity (<i>p</i> = 0.004, <i>d</i> = 1.33), kinesiophobia (<i>p</i> = 0.035, <i>d</i> = 1.15), and depression (<i>p</i> = 0.034, <i>d</i> = 1.08) were found in favour of the IG.</p> Conclusion <p>Data indicate that the multimodal intervention MultiMove improved clinical and functional outcomes in CLBP patients during inpatient rehabilitation. Therefore, conducting a randomized controlled trial with a large sample size is recommended to verify and extent these results.</p> Trial registration <p>MultiMove project (German Clinical Trial Register, ID: DRKS00021696 / 10.07.2020, <a href="https://drks.de/drks_web/navigate.do?navigationId=trial.HTML26TRIAL_ID=DRKS00021696">https://drks.de/drks_web/navigate.do?navigationId=trial.HTML26TRIAL_ID=DRKS00021696</a>) and was carried out in the rehabilitation clinic Bad Salzelmen (Schönebeck, Germany).</p>

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Effects of an additional multimodal intervention (MultiMove) during inpatient rehabilitation on clinical and functional outcomes in patients with chronic low back pain– a pilot trial

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  • 发表日期：

    2025年4月16日

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  • Toan Nguyen,
  • Martin Behrens,
  • Kim-Charline Broscheid,
  • Robert Bielitzki,
  • Kerstin Rohkohl,
  • Ivonne Rudolph,
  • Katharina Meiler,
  • Jörg Franke,
  • Lutz Schega

摘要

Background

As a leading cause of disability, chronic low back pain (CLBP) is a musculoskeletal condition often associated with impaired physical and cognitive functions. Due to its multi-factorial facets, the application of multimodal interventions is recommended. MultiMove is a multimodal intervention designed for CLBP patients, which combines motor-cognitive and dancing exercises. This study aimed to assess the effects of an additional MultiMove intervention to a standard inpatient rehabilitation on clinical and functional outcomes in CLBP patients.

Methods

For this prospective, two-arm, controlled pilot trial, 27 CLBP patients (17 females, 10 males) undergoing a 3-week inpatient rehabilitation, in a rehabilitation clinic in Germany, were recruited. The intervention group (IG, n = 15, 61.6 ± 1.8 years) received a daily MultiMove session in addition to the standard rehabilitation, while the control group (CG, n = 12, 63.8 ± 2.2 years) followed the standard rehabilitation. Physical (Timed Up and Go (TUG) [primary outcome], Five-Repetition Sit-to-Stand (FRSTS), and Six-Minute Walk Test (6MWT), trunk range of motion, single and dual task walking)), clinical (acute/chronic pain intensity, Oswestry Disability Index, EQ-5D-5 L), cognitive (Stroop Color Word Test, Trail Making Test), and psychosocial outcomes (Tampa Scale of Kinesiophobia, Beck Depression Inventory-II, Coping Strategies Questionnaire) were assessed during the first (pre-test) and last day (post-test) of the inpatient rehabilitation.

Results

The statistical analyses revealed improvements in trunk range of motion (sagittal plane: p = 0.018, d = 1.00; transversal plane: p = 0.006, d = 1.18) and 6MWT performance (p = 0.003, d = 1.30) in the IG compared to the CG. Moreover, lower dual task costs for a gait variability measure (p = 0.034, d = 0.97) as well as reduced chronic pain intensity (p = 0.004, d = 1.33), kinesiophobia (p = 0.035, d = 1.15), and depression (p = 0.034, d = 1.08) were found in favour of the IG.

Conclusion

Data indicate that the multimodal intervention MultiMove improved clinical and functional outcomes in CLBP patients during inpatient rehabilitation. Therefore, conducting a randomized controlled trial with a large sample size is recommended to verify and extent these results.

Trial registration

MultiMove project (German Clinical Trial Register, ID: DRKS00021696 / 10.07.2020, https://drks.de/drks_web/navigate.do?navigationId=trial.HTML26TRIAL_ID=DRKS00021696) and was carried out in the rehabilitation clinic Bad Salzelmen (Schönebeck, Germany).