Background <p>L<!--Query ID="Q1" Text="Please check if the article title is presented correctly. " Resolved="yes"-->ung and bronchus cancer remains the leading cause of cancer related mortality in the United States, yet the influence of climatic factors on incidence rates remains understudied. This research investigates the association between temperature, severe drought duration, and cancer incidence rates among Non-Hispanic (NH) Whites in Texas.</p> Methods <p>A cross-sectional<!--Query ID="Q2" Text="Please confirm if the author names are presented accurately. " Resolved="yes"--> population-based analysis using Texas Cancer Registry county-data (<i>n</i> = 98) for age-adjusted incidence rates of lung and bronchus cancer for NH Whites from 2013 to 2022. Annual ambient temperature data from NOAA and drought severity metrics from the US Drought Monitor were associated with cancer incidence rates. After controlling for key covariates, adjusted associations were conducted using Poisson regression and were stratified by various phases of drought periods. Adjusted associations were reported as incidence rate ratio (IRR).</p> Results <p>Findings i<!--Query ID="Q3" Text="Please check if affiliation were captured and presented correctly. Otherwise, kindly amend if necessary. " Resolved="yes"-->ndicate a significant interaction (<i>P</i> &lt; 0.05) between annual temperatures and the number of weeks of severe drought. Hence drought duration is found to be an associational effect modifier between cancer incidence and ambient temperature among all ages for NH Whites in Texas. Upon adjusted for covariates, each 1&#xa0;°F in annual temperatures increased the risk for lung and bronchus cancer incidence for droughts duration of ≤ 7 weeks [IRR 1.012 (1.001–1.023), <i>P</i> = 0.04] and ≥ 21 weeks [IRR 1.009 (1.001–1.017), <i>P</i> = 0.039] among NH Whites in Texas.</p> Conclusion <p>This study provides unique racial specific evidence linking climatic variables to lung and bronchus cancer. These findings contribute to a growing body of evidence suggesting that climate variability is a critical determinant of respiratory cancer outcomes.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Associations of lung and bronchus cancer incidence and ambient temperature and severe drought: a population-based study

  • Haris Majeed,
  • George Kypriotakis

摘要

Background

Lung and bronchus cancer remains the leading cause of cancer related mortality in the United States, yet the influence of climatic factors on incidence rates remains understudied. This research investigates the association between temperature, severe drought duration, and cancer incidence rates among Non-Hispanic (NH) Whites in Texas.

Methods

A cross-sectional population-based analysis using Texas Cancer Registry county-data (n = 98) for age-adjusted incidence rates of lung and bronchus cancer for NH Whites from 2013 to 2022. Annual ambient temperature data from NOAA and drought severity metrics from the US Drought Monitor were associated with cancer incidence rates. After controlling for key covariates, adjusted associations were conducted using Poisson regression and were stratified by various phases of drought periods. Adjusted associations were reported as incidence rate ratio (IRR).

Results

Findings indicate a significant interaction (P < 0.05) between annual temperatures and the number of weeks of severe drought. Hence drought duration is found to be an associational effect modifier between cancer incidence and ambient temperature among all ages for NH Whites in Texas. Upon adjusted for covariates, each 1 °F in annual temperatures increased the risk for lung and bronchus cancer incidence for droughts duration of ≤ 7 weeks [IRR 1.012 (1.001–1.023), P = 0.04] and ≥ 21 weeks [IRR 1.009 (1.001–1.017), P = 0.039] among NH Whites in Texas.

Conclusion

This study provides unique racial specific evidence linking climatic variables to lung and bronchus cancer. These findings contribute to a growing body of evidence suggesting that climate variability is a critical determinant of respiratory cancer outcomes.