Background <p>The Food System Transformative Integrated Policy (FS-TIP) is an evidence-based framework developed to identify key food system challenges, relevant policies, and the actors necessary to support food systems. Following pilot implementation in Ghana, Malawi, and Rwanda, this study evaluated the initiative by exploring perceptions of its relevance, stakeholder preparedness to implement the approach, the degree of stakeholder involvement, and the enablers and barriers influencing implementation.</p> Methods <p>This was a cross-sectional mixed methods study conducted in Ghana, Malawi and Rwanda. Data on willingness to adopt the process and perceived relevance of the initiative was collected using an online semi-structured questionnaire and key informant interviews were conducted to capture enablers and barriers. To assess the level of multi-stakeholder engagement, a desk review of process outputs was also conducted.</p> Results <p>Ten stakeholders (Ghana = 2, Malawi = 5, Rwanda = 3) completed the online survey, and twenty-five participants (Ghana = 10, Malawi = 6, Rwanda = 7, project management team = 2) took part in interviews. Respondents reported willingness to adopt FS-TIP, perceived it as relevant to the African context, and considered it policy-oriented, though challenging to implement. Facilitators of implementation included stakeholder buy-in, involvement of local experts, and access to routinely collected data, whereas barriers included limited centralized databases, restricted stakeholder engagement, and inadequate implementation time.</p> Conclusion <p>The FS-TIP initiative identified key food system challenges in Ghana, Malawi, and Rwanda. Stakeholders viewed the approach as relevant, acceptable, and feasible for adoption, with the potential to strengthen food system diagnostics and policy development. To promote long-term ownership and sustainability, the initiative would ideally be government-led and embedded within existing structures and initiatives.</p>