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Background and purpose <p>This study aims to explore whether different types of oral conditions are associated with incident stroke risk.</p> Methods and results <p>This cohort study included 476,868 individuals without outcome events at baseline, multivariable models <!--Query ID="Q1" Text="Please check article title if captured correctly." Resolved="yes"-->were constructed using Cox proportional hazard regression to assess the association between different oral conditions and the incidence of stroke, ischemic stroke (IS) and myocardial infarction (MI). Our fully adjusted model showed that individuals with painful gums [HR<sub>painful gums</sub>: 1.31 (1.06, 1.63)], loose teeth [HR<sub>loose teeth</sub>: 1.45 (1.20, 1.77)] and dentures [HR<sub>dentures</sub>: 1.23 (1.12, 1.36)] have increased risk for <!--Query ID="Q2" Text="Please confirm if the author names are presented accurately and in the correct sequence. Otherwise amend if necessary." Resolved="yes"-->stroke incidence.</p> Conclusions <p>Individuals with painful gums, loose teeth and dentures have increased risk for stroke, IS and MI incidence,<!--Query ID="Q3" Text="Please check if affiliations were captured and presented correctly." Resolved="yes"--> this study helps to identify high-risk stroke participants.</p>

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Associations between self-reported oral health and incident stroke: a prospective analysis of the UK Biobank

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月5日

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  • Chang-Qing Sun,
  • Hui-Min Liu,
  • Qian-Yu Zhou,
  • Meng-Ting Liu,
  • Jia-Jun Chen,
  • Peng Wang,
  • Hua Ye,
  • Qiang Zhang

摘要

Background and purpose

This study aims to explore whether different types of oral conditions are associated with incident stroke risk.

Methods and results

This cohort study included 476,868 individuals without outcome events at baseline, multivariable models were constructed using Cox proportional hazard regression to assess the association between different oral conditions and the incidence of stroke, ischemic stroke (IS) and myocardial infarction (MI). Our fully adjusted model showed that individuals with painful gums [HRpainful gums: 1.31 (1.06, 1.63)], loose teeth [HRloose teeth: 1.45 (1.20, 1.77)] and dentures [HRdentures: 1.23 (1.12, 1.36)] have increased risk for stroke incidence.

Conclusions

Individuals with painful gums, loose teeth and dentures have increased risk for stroke, IS and MI incidence, this study helps to identify high-risk stroke participants.