Scholarlink

<p>Excess visceral fat mass (VFM) is a key risk factor for metabolic diseases, and physical activity (PA) is a modifiable behavior associated with lower VFM. This cross-sectional study investigates the dose-response relationship between PA and VFM, with a focus on differences by sex and race/ethnicity, using data from the National Health and Nutrition Examination Survey (NHANES) 2011–2018. Among 9,111 adults aged 20–59 years, PA was measured as metabolic equivalent of task (MET) minutes per week via the Global Physical Activity Questionnaire (GPAQ) and categorized into quintiles (Q1: 0-280, Q2: 281-1,680, Q3: 1,681-5,400, Q4: 5,401 − 11,020, Q5: &gt;11,020 MET-min/week). VFM was assessed using dual-energy X-ray absorptiometry (DXA). Weighted linear regression and restricted cubic spline (RCS) models were employed to examine associations, adjusting for demographic (age, sex, race/ethnicity), lifestyle (smoking, alcohol, caloric intake), and health-related (BMI, diabetes, hypertension) covariates. Higher PA levels were associated with lower VFM ratios, with the highest quintile (Q5) having a 12% lower ratio compared to the lowest (Q1) (Ratio = 0.88, 95% CI: 0.85–0.91, <i>P</i> &lt; 0.001) after full adjustment.RCS analyses revealed sex-specific patterns: males exhibited a monotonic decrease in VFM up to 50,000 MET-min/week, while females showed a U-shaped association, with the lowest VFM at ~ 6,000 MET-min/week, suggesting moderate PA (~ 5,000–7,000 MET-min/week) as optimal. Significant interactions by sex (<i>P</i>_interaction = 0.008) and race/ethnicity (<i>P</i>_interaction &lt; 0.001) highlighted heterogeneity: Non-Hispanic Whites showed a consistent VFM decline, while Mexican Americans exhibited a weaker association with An inverted U-shape, peaking at 1,000–3,000 MET-min/week. These findings underscore the need for tailored PA recommendations by sex and race/ethnicity. The cross-sectional design precludes causal inference.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Dose-response relationship between physical activity and visceral fat mass: a cross-sectional study based on NHANES 2011–2018

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月24日

查看全文
  • Jiancheng Bo,
  • Mingyue Yang

摘要

Excess visceral fat mass (VFM) is a key risk factor for metabolic diseases, and physical activity (PA) is a modifiable behavior associated with lower VFM. This cross-sectional study investigates the dose-response relationship between PA and VFM, with a focus on differences by sex and race/ethnicity, using data from the National Health and Nutrition Examination Survey (NHANES) 2011–2018. Among 9,111 adults aged 20–59 years, PA was measured as metabolic equivalent of task (MET) minutes per week via the Global Physical Activity Questionnaire (GPAQ) and categorized into quintiles (Q1: 0-280, Q2: 281-1,680, Q3: 1,681-5,400, Q4: 5,401 − 11,020, Q5: >11,020 MET-min/week). VFM was assessed using dual-energy X-ray absorptiometry (DXA). Weighted linear regression and restricted cubic spline (RCS) models were employed to examine associations, adjusting for demographic (age, sex, race/ethnicity), lifestyle (smoking, alcohol, caloric intake), and health-related (BMI, diabetes, hypertension) covariates. Higher PA levels were associated with lower VFM ratios, with the highest quintile (Q5) having a 12% lower ratio compared to the lowest (Q1) (Ratio = 0.88, 95% CI: 0.85–0.91, P < 0.001) after full adjustment.RCS analyses revealed sex-specific patterns: males exhibited a monotonic decrease in VFM up to 50,000 MET-min/week, while females showed a U-shaped association, with the lowest VFM at ~ 6,000 MET-min/week, suggesting moderate PA (~ 5,000–7,000 MET-min/week) as optimal. Significant interactions by sex (P_interaction = 0.008) and race/ethnicity (P_interaction < 0.001) highlighted heterogeneity: Non-Hispanic Whites showed a consistent VFM decline, while Mexican Americans exhibited a weaker association with An inverted U-shape, peaking at 1,000–3,000 MET-min/week. These findings underscore the need for tailored PA recommendations by sex and race/ethnicity. The cross-sectional design precludes causal inference.