Scholarlink

Obejective <p>To examine the correlations of pre-pregnancy Body-Mass-Index (BMI) and Gestational Weight Gain (GWG) with preterm singleton delivery among American women with cervical cerclage.</p> Methods <p>This is a retrospective cohort study of 33822 pregnant women with cervical cerclage selected from the National Vital Statistics System (NVSS) 2009–2013 database. GWG was converted to gestational age-standardized z scores. Associations of pre-pregnancy BMI and GWG with preterm birth risk were evaluated using risk factor–adjusted log-binomial regression models.</p> Results <p>Preterm birth accounted for 10378 (30.68%) of the pregnancies in our research. Women with pre-pregnancy overweight and obesity were both associated with a significantly higher risk of preterm birth than those with normal weight (RR(95% CI): 1.06(1.02,1.10), <i>P</i> = 0.007;RR(95% CI): 1.13(1.09,1.17), <i>P</i> &lt; 0.001). Preterm birth risks were higher in pre-pregnancy underweight women with low GWG z scores (RR(95% CI): 1.52(1.26,1.84), <i>P</i> &lt; 0.001). Among pre-pregnancy normal-weight women, those with low (RR(95% CI): 1.17(1.10,1.24), <i>P</i> &lt; 0.001) or high (RR(95% CI): 1.23(1.14,1.33, <i>P</i> &lt; 0.001) GWG z scores both had an increased risk of preterm birth. Preterm birth risks were higher in women with pre-pregnancy overweight when they had high GWG z scores (RR(95% CI): 1.20(1.10,1.32), <i>P</i> &lt; 0.001). Among women with pre-pregnancy obesity, those with high GWG z scores had increased preterm birth risks (RR(95% CI): 1.20(1.14,1.27), <i>P</i> &lt; 0.001). Notably, there was a significant reduction in preterm birth risk among women with low GWG z scores in the pre-pregnancy obesity group (RR(95% CI): 0.88(0.81,0.95), <i>P</i> = 0.002).</p> Conclusions <p>Pregnant women with cervical cerclage should maintain an appropriate weight before and during pregnancy, suggesting that more tailored weight control and prenatal care should be provided to pregnant women according to their pre-pregnancy BMI.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Association of pre-pregnancy body-mass-index and gestational weight gain with preterm singleton birth in women with cervical cerclage: a retrospective cohort study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月28日

查看全文
  • Zhaorui Wang,
  • Jing Tang,
  • Ao Zhang,
  • Zhuoyao Mai,
  • Rouhua Xu,
  • Qingxue Zhang,
  • Wulan Cao,
  • Yihong Guo,
  • Yang Zhou,
  • Nengyong Ouyang,
  • Hui Chen

摘要

Obejective

To examine the correlations of pre-pregnancy Body-Mass-Index (BMI) and Gestational Weight Gain (GWG) with preterm singleton delivery among American women with cervical cerclage.

Methods

This is a retrospective cohort study of 33822 pregnant women with cervical cerclage selected from the National Vital Statistics System (NVSS) 2009–2013 database. GWG was converted to gestational age-standardized z scores. Associations of pre-pregnancy BMI and GWG with preterm birth risk were evaluated using risk factor–adjusted log-binomial regression models.

Results

Preterm birth accounted for 10378 (30.68%) of the pregnancies in our research. Women with pre-pregnancy overweight and obesity were both associated with a significantly higher risk of preterm birth than those with normal weight (RR(95% CI): 1.06(1.02,1.10), P = 0.007;RR(95% CI): 1.13(1.09,1.17), P < 0.001). Preterm birth risks were higher in pre-pregnancy underweight women with low GWG z scores (RR(95% CI): 1.52(1.26,1.84), P < 0.001). Among pre-pregnancy normal-weight women, those with low (RR(95% CI): 1.17(1.10,1.24), P < 0.001) or high (RR(95% CI): 1.23(1.14,1.33, P < 0.001) GWG z scores both had an increased risk of preterm birth. Preterm birth risks were higher in women with pre-pregnancy overweight when they had high GWG z scores (RR(95% CI): 1.20(1.10,1.32), P < 0.001). Among women with pre-pregnancy obesity, those with high GWG z scores had increased preterm birth risks (RR(95% CI): 1.20(1.14,1.27), P < 0.001). Notably, there was a significant reduction in preterm birth risk among women with low GWG z scores in the pre-pregnancy obesity group (RR(95% CI): 0.88(0.81,0.95), P = 0.002).

Conclusions

Pregnant women with cervical cerclage should maintain an appropriate weight before and during pregnancy, suggesting that more tailored weight control and prenatal care should be provided to pregnant women according to their pre-pregnancy BMI.