Background <p>The Specific Phobia of Vomiting Inventory (SPOVI) is a 14-item instrument measuring behavioral avoidance and threat monitoring associated with emetophobia. The current study aimed to provide a German translation of the SPOVI and examine its psychometric properties and correlates.</p> Methods <p><i>N</i> = 441 adults from the general population and <i>N</i> = 465 outpatients with mental disorders completed the SPOVI and other self-report measures. Factor structure, reliability, convergent, and discriminant validity, as well as clinical utility, were investigated.</p> Results <p>The German version of the SPOVI had a one-factor structure and high internal consistency in both samples (ωs &gt; 0.90). Large correlations (<i>rs</i> &gt; 0.50) with questionnaires assessing phobic anxiety, general anxiety, illness-related anxiety, and disgust sensitivity supported convergent validity, while relatively low correlations with questionnaires assessing depression, eating disorders or paranoid ideation supported discriminant validity. Among outpatients, those with a specific phobia diagnosis had the highest SPOVI scores.</p> Conclusion <p>The German translation of the SPOVI has sound psychometric properties and is a potentially practical clinical screening instrument for emetophobia.</p> Pre-registration <p><a href="https://aspredicted.org/5y6zb.pdf">https://aspredicted.org/5y6zb.pdf</a>.</p>