Scholarlink

Background <p>Anemia in newborns is a complex health problem posing immediate life-threatening and long-term complications, and it is considered a serious global public health problem, particularly in African countries. Due to significant geographical variations in anemia prevalence across different African countries, inconsistencies between study findings were notably increased. Therefore, this study aimed to assess the pooled prevalence and its associated factors of anemia among newborns in Africa.</p> Methods <p>This systematic review and meta-analysis was registered with PROSPERO (CRD42024608059) and conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive and structured search was carried out in PubMed, CINAHL, Scopus, ScienceDirect, HINARI, and Web of Science, covering all literature available up to July 20, 2025. A meta-analysis using a random-effects model was performed. The heterogeneity of studies was assessed using I<sup>2</sup> statistics, and to identify the possible causes of heterogeneity, subgroup analysis and meta-regression were used. Egger’s test and funnel plots were used to evaluate a publication bias. STATA version 17.0 software was used for data analysis, and a <i>p</i>-value &lt; 0.05 was used to declare a statistical significance.</p> Results <p>Fourteen articles with 4488 newborns were included in this systematic review and meta-analysis. This review found that the prevalence of anemia among newborns in Africa was found to be 30.52% (95% CI: 22.92, 38.11) (I<sup>2</sup> = 96.94%). The subgroup analysis using the regions of the continent showed that the lowest prevalence was observed in East Africa (23.48%; 95% CI: 19.01, 27.96) (I<sup>2</sup> = 84.82%), followed by West Africa (39.46%; 95% CI: 14.58, 64.34) (I<sup>2</sup> = 99.16%). Insufficient vegetable consumption (OR: 3.22, 95% CI: 1.93, 5.37), maternal anemia (OR: 2.94, 95% CI: 1.55, 5.58), lack of iron supplementation during pregnancy (OR: 2.66, 95% CI: 1.35, 5.23), and having a history of antepartum hemorrhage (APH) (OR: 2.26, 95% CI: 1.39, 3.66) were factors associated with anemia among newborns in Africa.</p> Conclusion and recommendations <p>Anemia remains a significant public health concern in Africa, with approximately one-third of newborns affected. Maternal anemia, insufficient vegetable consumption, lack of iron supplementation during pregnancy, and a history of antepartum hemorrhage were significantly associated with anemia among newborns.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Prevalence and associated factors of anemia among newborns in Africa: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月6日

查看全文
  • Mengistu Abebe Messelu,
  • Baye Tsegaye Amlak,
  • Tadesse Yirga Akalu,
  • Bekele Getenet Tiruneh,
  • Mulualem Biazen Adugna,
  • Abiyie Zeleke,
  • Makda Fekadie Tewelgne,
  • Aster Tadesse Shibabaw,
  • Getnet Nibret,
  • Salelign Amlaku,
  • Temesgen Ayenew

摘要

Background

Anemia in newborns is a complex health problem posing immediate life-threatening and long-term complications, and it is considered a serious global public health problem, particularly in African countries. Due to significant geographical variations in anemia prevalence across different African countries, inconsistencies between study findings were notably increased. Therefore, this study aimed to assess the pooled prevalence and its associated factors of anemia among newborns in Africa.

Methods

This systematic review and meta-analysis was registered with PROSPERO (CRD42024608059) and conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive and structured search was carried out in PubMed, CINAHL, Scopus, ScienceDirect, HINARI, and Web of Science, covering all literature available up to July 20, 2025. A meta-analysis using a random-effects model was performed. The heterogeneity of studies was assessed using I2 statistics, and to identify the possible causes of heterogeneity, subgroup analysis and meta-regression were used. Egger’s test and funnel plots were used to evaluate a publication bias. STATA version 17.0 software was used for data analysis, and a p-value < 0.05 was used to declare a statistical significance.

Results

Fourteen articles with 4488 newborns were included in this systematic review and meta-analysis. This review found that the prevalence of anemia among newborns in Africa was found to be 30.52% (95% CI: 22.92, 38.11) (I2 = 96.94%). The subgroup analysis using the regions of the continent showed that the lowest prevalence was observed in East Africa (23.48%; 95% CI: 19.01, 27.96) (I2 = 84.82%), followed by West Africa (39.46%; 95% CI: 14.58, 64.34) (I2 = 99.16%). Insufficient vegetable consumption (OR: 3.22, 95% CI: 1.93, 5.37), maternal anemia (OR: 2.94, 95% CI: 1.55, 5.58), lack of iron supplementation during pregnancy (OR: 2.66, 95% CI: 1.35, 5.23), and having a history of antepartum hemorrhage (APH) (OR: 2.26, 95% CI: 1.39, 3.66) were factors associated with anemia among newborns in Africa.

Conclusion and recommendations

Anemia remains a significant public health concern in Africa, with approximately one-third of newborns affected. Maternal anemia, insufficient vegetable consumption, lack of iron supplementation during pregnancy, and a history of antepartum hemorrhage were significantly associated with anemia among newborns.