Scholarlink

Background <p>The aim of the present study was to compare the rates of change in Ganglion Cell- Inner Plexiform Layer (GCIPL) and Retinal Nerve Fiber Layer (RNFL) thickness, as measured by Optical Coherence Tomography (OCT) Guided Progression Analysis (GPA) program in control group, Primary Open Angle Glaucoma (POAG) and Pseudoexfoliation Glaucoma (PXG) eyes.</p> Methods <p>60 POAG and 60 PXG patients and 30 control group patients were included in the study. Patients diagnosed with glaucoma were divided into two groups as mild (Mean deviation (MD) &gt; -6.00) and moderate-severe (MD &lt; -6.00). The average, superior and inferior quadrant thinning rates (expressed in micrometers per year) of GCIPL and RNFL in the OCT GPA program were compared between groups.</p> Results <p>Average GCIPL thinning rates were -0.23 ± 0.21 μm/year in the control group, -0.64 ± 0.54 μm/year in POAG patients, and -1.06 ± 1.16 μm/year in PXG patients (ANOVA, <i>p</i> &lt; 0.001). Average RNFL thinning rates were -0.33 ± 0.44 μm/year in the control group, -0.86 ± 0.73 μm/year in POAG patients, and -1.33 ± 1.4 μm/year in PXG patients (ANOVA, <i>p</i> &lt; 0.001).</p> Conclusions <p>The rates of GCIPL and RNFL thinning were highest in patients with PXG.</p> <p>We found that the glaucoma stage did not affect the rate of RNFL and GCIPL thinning.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Comparison of glaucoma progression rate in glaucoma patients at different stages using guided progression analysis with optical coherence tomography

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年1月2日

查看全文
  • Okan Akmaz,
  • Murat Gokhan Tokac,
  • Murat Garli,
  • Tuncay Kusbeci

摘要

Background

The aim of the present study was to compare the rates of change in Ganglion Cell- Inner Plexiform Layer (GCIPL) and Retinal Nerve Fiber Layer (RNFL) thickness, as measured by Optical Coherence Tomography (OCT) Guided Progression Analysis (GPA) program in control group, Primary Open Angle Glaucoma (POAG) and Pseudoexfoliation Glaucoma (PXG) eyes.

Methods

60 POAG and 60 PXG patients and 30 control group patients were included in the study. Patients diagnosed with glaucoma were divided into two groups as mild (Mean deviation (MD) > -6.00) and moderate-severe (MD < -6.00). The average, superior and inferior quadrant thinning rates (expressed in micrometers per year) of GCIPL and RNFL in the OCT GPA program were compared between groups.

Results

Average GCIPL thinning rates were -0.23 ± 0.21 μm/year in the control group, -0.64 ± 0.54 μm/year in POAG patients, and -1.06 ± 1.16 μm/year in PXG patients (ANOVA, p < 0.001). Average RNFL thinning rates were -0.33 ± 0.44 μm/year in the control group, -0.86 ± 0.73 μm/year in POAG patients, and -1.33 ± 1.4 μm/year in PXG patients (ANOVA, p < 0.001).

Conclusions

The rates of GCIPL and RNFL thinning were highest in patients with PXG.

We found that the glaucoma stage did not affect the rate of RNFL and GCIPL thinning.