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Objective <p>In this study, we retrospectively analyzed the incidence of and risk factors for in-hospital venous thromboembolism (VTE) in patients with bladder cancer and explored measures to reduce the incidence of and/or prevent in-hospital VTE and mortality.</p> Methods <p>The clinical data of 5744 patients with bladder cancer who were admitted to the Second Hospital of Tianjin Medical University during a 5-year period were summarized and then analyzed to determine the risk factors for in-hospital VTE in patients with bladder cancer with the aim of identifying preventive measures.</p> Results <p>Univariate analysis revealed significant differences between the VTE group and the non-VTE group in terms of age, sex, Caprini score, surgical treatment status, tumor stage, D-dimer level, PT, APTT, and Hb (<i>P</i> &lt; 0.05). Multiple factor analysis further confirmed that the Caprini score, surgical treatment status, D-dimer level, PT, and APTT were independent risk factors for VTE.</p> Conclusion <p>Analyses revealed that a high Caprini score, surgical treatment, an elevated D-dimer level, a short PT, and a short APTT were independent risk factors for in-hospital VTE in patients with bladder cancer and that active preventive measures should be implemented to reduce the incidence of in-hospital VTE as well as mortality.</p>

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Risk factors for in-hospital venous thromboembolism in patients with bladder cancer: A retrospective single-center study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月24日

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  • Huitang Yang,
  • Tonghe Zhang,
  • Zhaoyang Li,
  • Yandong Cai,
  • Zhan Jiang,
  • Guoju Fan,
  • Kaiqiang Wang,
  • Bo Chen,
  • Hongwei Zhang,
  • Hailong Hu,
  • Yankui Li

摘要

Objective

In this study, we retrospectively analyzed the incidence of and risk factors for in-hospital venous thromboembolism (VTE) in patients with bladder cancer and explored measures to reduce the incidence of and/or prevent in-hospital VTE and mortality.

Methods

The clinical data of 5744 patients with bladder cancer who were admitted to the Second Hospital of Tianjin Medical University during a 5-year period were summarized and then analyzed to determine the risk factors for in-hospital VTE in patients with bladder cancer with the aim of identifying preventive measures.

Results

Univariate analysis revealed significant differences between the VTE group and the non-VTE group in terms of age, sex, Caprini score, surgical treatment status, tumor stage, D-dimer level, PT, APTT, and Hb (P < 0.05). Multiple factor analysis further confirmed that the Caprini score, surgical treatment status, D-dimer level, PT, and APTT were independent risk factors for VTE.

Conclusion

Analyses revealed that a high Caprini score, surgical treatment, an elevated D-dimer level, a short PT, and a short APTT were independent risk factors for in-hospital VTE in patients with bladder cancer and that active preventive measures should be implemented to reduce the incidence of in-hospital VTE as well as mortality.