Objective <p>To understand the current situation of knowledge, attitude and practice of breast engorgement in postpartum women and analyze its influencing factors.</p> Methods <p>From August 2019 to December 2019, by using the method of convenient sampling, 530 postpartum women in the department of obstetrics in 3 tertiary hospitals were investigated with the breast engorgement knowledge, attitude and practice and general data questionnaire. </p> Results <p>The scores of breast engorgement of knowledge, attitude, practice and total KAP were (8.90 ± 3.17), (33.83 ± 3.54), (31.67 ± 1.41) and (74.41 ± 12.26). The results of regression analysis showed that participation in school during pregnancy and knew breast engorgement were influencing factors of breast engorgement knowledge score. Graduate and above (maternity), participation in school during pregnancy and vaginal delivery were influencing factors of attitude score towards breast engorgement. Artificial feeding and mixed feeding were influencing factor of practice score of breast engorgement. Participation in school during pregnancy, knew breast engorgement, artificial feeding, mixed feeding and commercial and service personnel (spouse) were influencing factors of total score of KAP of breast engorgement (<i>P</i>&lt;0.05). </p> Conclusion <p>The level of knowledge about breast engorgement is low, the attitude towards breast engorgement is positive, and the practice to breast engorgement need to be improved. Health care workers should formulate and implement targeted nursing education and intervention to improve the level of knowledge, attitude and practice of breast engorgement in order to reduce the incidence of breast engorgement.</p>