Scholarlink

Objective <p>To investigate the clinical characteristics and CTA imaging features of radiation-induced carotid artery pseudoaneurysm (CAPA) in patients with nasopharyngeal carcinoma (NPC).</p> Methods <p>We retrospectively analyzed 22 NPC patients with CAPA confirmed by DSA after radiotherapy. Clinical data and CTA findings were reviewed.</p> Results <p>All patients presented with anemia; 81.8% experienced massive epistaxis. CAPAs were predominantly solitary (90.9%) and located in the internal carotid artery, especially the C3 segment. CTA revealed pseudoaneurysm morphology, adjacent tissue necrosis, osteoradionecrosis, and parent artery stenosis. The rebleeding rate within 3 months was 31.8%, and the mortality rate was 18.2%. Low BMI were associated with worse outcomes.</p> Conclusion <p>CAPA is a life-threatening but detectable complication in post-radiotherapy NPC patients. CTA facilitates early identification of vascular injury and supports timely intervention planning; however, despite timely detection and endovascular treatment, the short-term prognosis of CAPA remains poor.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Clinical features and CTA imaging of radiation-induced carotid pseudoaneurysms in nasopharyngeal carcinoma

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月6日

查看全文
  • Yuanling Yang,
  • Xinting Peng,
  • Yifan Xu,
  • Weiyi Liu,
  • Zisan Zeng

摘要

Objective

To investigate the clinical characteristics and CTA imaging features of radiation-induced carotid artery pseudoaneurysm (CAPA) in patients with nasopharyngeal carcinoma (NPC).

Methods

We retrospectively analyzed 22 NPC patients with CAPA confirmed by DSA after radiotherapy. Clinical data and CTA findings were reviewed.

Results

All patients presented with anemia; 81.8% experienced massive epistaxis. CAPAs were predominantly solitary (90.9%) and located in the internal carotid artery, especially the C3 segment. CTA revealed pseudoaneurysm morphology, adjacent tissue necrosis, osteoradionecrosis, and parent artery stenosis. The rebleeding rate within 3 months was 31.8%, and the mortality rate was 18.2%. Low BMI were associated with worse outcomes.

Conclusion

CAPA is a life-threatening but detectable complication in post-radiotherapy NPC patients. CTA facilitates early identification of vascular injury and supports timely intervention planning; however, despite timely detection and endovascular treatment, the short-term prognosis of CAPA remains poor.