<p>Melioidosis, caused by the gram-negative facultative intracellular bacterium <i>Burkholderia pseudomallei</i>, is a complex and variable disease with a broad spectrum of clinical manifestations. It is primarily transmitted through exposure to wet-season soils or contaminated water. This case series presents five patients diagnosed with melioidosis, highlighting their diverse clinical presentations, diagnostic challenges, treatment approaches, and outcomes. The discussion includes a review of current literature on the epidemiology, pathogenesis, and management of melioidosis.</p>

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Melioidosis: diverse clinical manifestations and patient outcomes in a case series

  • Ravi Kishor Allu,
  • Raviteja Nalabothula,
  • Kamala Kannan,
  • Kumar Janardhanan Subramonia,
  • Vaishnavi R

摘要

Melioidosis, caused by the gram-negative facultative intracellular bacterium Burkholderia pseudomallei, is a complex and variable disease with a broad spectrum of clinical manifestations. It is primarily transmitted through exposure to wet-season soils or contaminated water. This case series presents five patients diagnosed with melioidosis, highlighting their diverse clinical presentations, diagnostic challenges, treatment approaches, and outcomes. The discussion includes a review of current literature on the epidemiology, pathogenesis, and management of melioidosis.