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Background <p>The coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges to global public health, particularly affecting nursing professionals, owing to their continuous exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and intense working conditions. This study aims to analyze the frequency and predictors of symptoms persisting for 4 weeks or more after COVID-19 among Brazilian nurses, examining associations with situational and clinical variables.</p> Methods <p>A cross-sectional study was conducted involving 3,155 nurses from all macroregions of Brazil who tested positive for COVID-19, of whom 1,921 reported persistent symptoms lasting four weeks or more due to COVID-19. Data collection included sociodemographic, situational, and clinical variables. The statistical tests chi-square was applied to assess differences between independent variables and symptom persistence. Additionally, in order to assess associations between the outcome variable and independent variables a logistic regression were applied. Finally co-occurrence analysis and the Jaccard index were used to identify patterns associated with persistency of COVID-19 symptoms.</p> Results <p>The study consisted of 3,155 nurses, predominantly female (84.0%). The prevalence of symptoms persisting for four weeks or longer after COVID-19 through the sample was 60,9%. Chronic conditions were reported by 33.0% of the participants, the most common persistent symptoms included fatigue (70.0%), memory loss (68.8%). Statistically significant associations were observed between long COVID-19 duration and the presence of comorbidities, especially rhinitis and obesity (<i>p</i> &lt; 0.01). Cooccurrence analysis revealed strong correlations between cough and memory loss (Jaccard = 0.980), insomnia and loss of taste (0.978).</p> Conclusions <p>The findings highlight the complexity of COVID-19 among Brazilian nurses and identify clinical and sociodemographic factors associated with persistent symptoms, informing strategies to support affected healthcare professionals.</p> Clinical trial number <p>Not applicable.</p>

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Prevalence and predictive factors of long COVID in nurses in Brazil

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月28日

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  • José Francisco Martoreli Júnior,
  • Laelson Rochelle Milanês Sousa,
  • Andrey Oeiras Pedroso,
  • Laís do Espírito Santo Lima,
  • Cristine Maria Pereira Gusmão,
  • Cristina Mara Zamarioli,
  • Mayra Gonçalves Menegueti,
  • Ana Cristina de Oliveira e Silva,
  • Glenda Roberta Oliveira Naiff Ferreira,
  • Elucir Gir,
  • Renata Karina Reis

摘要

Background

The coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges to global public health, particularly affecting nursing professionals, owing to their continuous exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and intense working conditions. This study aims to analyze the frequency and predictors of symptoms persisting for 4 weeks or more after COVID-19 among Brazilian nurses, examining associations with situational and clinical variables.

Methods

A cross-sectional study was conducted involving 3,155 nurses from all macroregions of Brazil who tested positive for COVID-19, of whom 1,921 reported persistent symptoms lasting four weeks or more due to COVID-19. Data collection included sociodemographic, situational, and clinical variables. The statistical tests chi-square was applied to assess differences between independent variables and symptom persistence. Additionally, in order to assess associations between the outcome variable and independent variables a logistic regression were applied. Finally co-occurrence analysis and the Jaccard index were used to identify patterns associated with persistency of COVID-19 symptoms.

Results

The study consisted of 3,155 nurses, predominantly female (84.0%). The prevalence of symptoms persisting for four weeks or longer after COVID-19 through the sample was 60,9%. Chronic conditions were reported by 33.0% of the participants, the most common persistent symptoms included fatigue (70.0%), memory loss (68.8%). Statistically significant associations were observed between long COVID-19 duration and the presence of comorbidities, especially rhinitis and obesity (p < 0.01). Cooccurrence analysis revealed strong correlations between cough and memory loss (Jaccard = 0.980), insomnia and loss of taste (0.978).

Conclusions

The findings highlight the complexity of COVID-19 among Brazilian nurses and identify clinical and sociodemographic factors associated with persistent symptoms, informing strategies to support affected healthcare professionals.

Clinical trial number

Not applicable.