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Background <p>COVID-19 vaccination is essential for pandemic control in low-resource settings such as Ghana, where uptake is influenced by sociodemographic and community factors. This study examined the factors associated with COVID-19 vaccine uptake among residents of the Kwahu South Municipality in the Eastern Region of Ghana.</p> Methods <p>A community-based cross-sectional study was conducted on 384 adults aged ≥ 18 years. Data on sociodemographic characteristics, COVID-19 knowledge, and community-related factors were collected using a structured questionnaire. Differences between variables were assessed using chi-square tests and multivariable logistic regression was performed to identify independent factors associated with COVID-19 vaccine uptake at a 5% significance level.</p> Results <p>Higher education significantly increased COVID-19 vaccine uptake (AOR = 3.0, [3.55–6.12]), as did prior COVID-19 infection (AOR = 10.2, [7.1-13.65]), awareness of COVID-19 vaccine (AOR = 8.3, [6.1–10.9]) and previous vaccination experience (AOR = 7.9, [3.32–11.77]). In contrast, scepticism about vaccine effectiveness substantially reduced uptake (AOR = 12.0, [9.46–14.93]).</p> Conclusion <p>COVID-19 vaccine uptake in Kwahu South Municipality was 76.6%, influenced by prior COVID-19 testing, vaccine awareness, previous vaccination and perceived effectiveness. Those with prior testing and awareness of COVID-19 vaccines were more likely to be vaccinated, while doubts about the vaccine’s effectiveness reduced uptake. This highlights the role of health engagement and perceptions in vaccination behavior.</p>

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Factors associated with COVID-19 vaccine uptake among residents of the Kwahu South Municipality in the Eastern Region of Ghana

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月13日

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  • Gifty Love Asabekah,
  • David Mensah Otoo,
  • Ebenezer Efichie,
  • Diana Ayinpokbila Akila,
  • Naomi Hagan,
  • Anthony Zunuo Dongdem

摘要

Background

COVID-19 vaccination is essential for pandemic control in low-resource settings such as Ghana, where uptake is influenced by sociodemographic and community factors. This study examined the factors associated with COVID-19 vaccine uptake among residents of the Kwahu South Municipality in the Eastern Region of Ghana.

Methods

A community-based cross-sectional study was conducted on 384 adults aged ≥ 18 years. Data on sociodemographic characteristics, COVID-19 knowledge, and community-related factors were collected using a structured questionnaire. Differences between variables were assessed using chi-square tests and multivariable logistic regression was performed to identify independent factors associated with COVID-19 vaccine uptake at a 5% significance level.

Results

Higher education significantly increased COVID-19 vaccine uptake (AOR = 3.0, [3.55–6.12]), as did prior COVID-19 infection (AOR = 10.2, [7.1-13.65]), awareness of COVID-19 vaccine (AOR = 8.3, [6.1–10.9]) and previous vaccination experience (AOR = 7.9, [3.32–11.77]). In contrast, scepticism about vaccine effectiveness substantially reduced uptake (AOR = 12.0, [9.46–14.93]).

Conclusion

COVID-19 vaccine uptake in Kwahu South Municipality was 76.6%, influenced by prior COVID-19 testing, vaccine awareness, previous vaccination and perceived effectiveness. Those with prior testing and awareness of COVID-19 vaccines were more likely to be vaccinated, while doubts about the vaccine’s effectiveness reduced uptake. This highlights the role of health engagement and perceptions in vaccination behavior.