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Background <p>Gonorrhoea is an infection caused by <i>Neisseria gonorrhoeae</i>. It is considered a significant public health problem. Asymptomatic infections are common, especially in women, and can lead to systemic dissemination.</p> Case presentation <p>We discuss a unique case of a 48-year old woman presenting with disseminated gonococcal infection (DGI) complicated by pleural and pericardial effusions. Microbiological confirmation was obtained by <i>N. gonorrhoeae</i> polymerase chain reaction on pleural fluid. The patient was successfully treated with intravenous ceftriaxone and pleural drainage. We provide a comprehensive review of the literature on gonococcal pleuritis and pericarditis. Both are rare complications of (DGI), but the combination has never been described in literature.</p> Conclusion <p>This case highlights the importance of early recognition and treatment of gonorrhoea and DGI to prevent severe complications.</p> Clinical trial <p>Not applicable.</p>

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A rare presentation of disseminated gonococcal infection with pleuritis and pericarditis: a case report and comprehensive review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月10日

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  • Reon Togo,
  • Joyce Vandersnickt,
  • Simone van der Sar-van der Brugge,
  • Janneke S. Hoogstad-van Evert,
  • Wouter van den Bijllaardt,
  • Peter van Wijngaarden

摘要

Background

Gonorrhoea is an infection caused by Neisseria gonorrhoeae. It is considered a significant public health problem. Asymptomatic infections are common, especially in women, and can lead to systemic dissemination.

Case presentation

We discuss a unique case of a 48-year old woman presenting with disseminated gonococcal infection (DGI) complicated by pleural and pericardial effusions. Microbiological confirmation was obtained by N. gonorrhoeae polymerase chain reaction on pleural fluid. The patient was successfully treated with intravenous ceftriaxone and pleural drainage. We provide a comprehensive review of the literature on gonococcal pleuritis and pericarditis. Both are rare complications of (DGI), but the combination has never been described in literature.

Conclusion

This case highlights the importance of early recognition and treatment of gonorrhoea and DGI to prevent severe complications.

Clinical trial

Not applicable.