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Objective <p>This cross-sectional study aimed to investigate the symptoms following COVID-19 infection among pediatric and adult allergic rhinitis (AR) patients undergoing different treatment regimens—specifically sublingual immunotherapy (SLIT) versus conventional pharmacological treatment.</p> Methods <p>A total of 398 patients diagnosed with AR were included from the clinical database and categorized according to treatment type: an SLIT group (AR-S), further stratified into AR-S1 (&lt; 18 years) and AR-S2 (≥ 18 years), and a control group (AR-C). Between December 2022 and February 2023, data on respiratory and general symptoms following SARS-CoV-2 infection were collected and compared across groups.</p> Results <p>The AR-S1 group may be associated with a reduced risk of symptoms after infection including dry throat (OR = 0.373, 95%Cl:0.184–0.755), headache (OR = 0.385, 95%Cl:0.196–0.758), fatigue (OR = 0.376, 95%Cl:0.188–0.751), chest tightness (OR = 0.160, 95%Cl:0.049–0.522), and some symptoms after improvement of infection (cough, fatigue).</p> Conclusion <p>Minor AR patients with SLIT can reduce some of the symptoms in COVID-19-infected patients.</p>

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Desensitization reduces some COVID-19-associated symptoms in minors with allergic rhinitis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月13日

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  • Shipeng Zhang,
  • Mengni Zhang,
  • Qiqi Liu,
  • Xiaocui Wang,
  • Junyu Xiang,
  • Qinxiu Zhang,
  • Min Hu

摘要

Objective

This cross-sectional study aimed to investigate the symptoms following COVID-19 infection among pediatric and adult allergic rhinitis (AR) patients undergoing different treatment regimens—specifically sublingual immunotherapy (SLIT) versus conventional pharmacological treatment.

Methods

A total of 398 patients diagnosed with AR were included from the clinical database and categorized according to treatment type: an SLIT group (AR-S), further stratified into AR-S1 (< 18 years) and AR-S2 (≥ 18 years), and a control group (AR-C). Between December 2022 and February 2023, data on respiratory and general symptoms following SARS-CoV-2 infection were collected and compared across groups.

Results

The AR-S1 group may be associated with a reduced risk of symptoms after infection including dry throat (OR = 0.373, 95%Cl:0.184–0.755), headache (OR = 0.385, 95%Cl:0.196–0.758), fatigue (OR = 0.376, 95%Cl:0.188–0.751), chest tightness (OR = 0.160, 95%Cl:0.049–0.522), and some symptoms after improvement of infection (cough, fatigue).

Conclusion

Minor AR patients with SLIT can reduce some of the symptoms in COVID-19-infected patients.