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<p>Parapneumonic effusions and empyema usually occur after bacterial pneumonia. Inflammation plays an essential role in the occurrence of pneumonia and can lead to an autoinflammatory condition. In this study, we will present three cases including multi-organ involvement following pleural empyema that have been treated with pulse corticosteroid therapy. Apparently, pleural empyema can lead to multi-organ involvement due to underlying inflammatory processes. This condition is usually associated with symptoms and changes in laboratory parameters that manifest after empyema treatment or reappear after temporary recovery. Hence, managing this condition by pulse corticosteroid therapy can result in positive outcomes.</p>

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The role of high dose corticosteroid (methylperednisolone pulse therapy) in treatment of multi-organ involvement after bacterial pneumonia and pleural empyema; “case series”

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月14日

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  • Seyed Hossein Mirlohi,
  • Sanaz Tajfirooz,
  • Mitra Rouhi

摘要

Parapneumonic effusions and empyema usually occur after bacterial pneumonia. Inflammation plays an essential role in the occurrence of pneumonia and can lead to an autoinflammatory condition. In this study, we will present three cases including multi-organ involvement following pleural empyema that have been treated with pulse corticosteroid therapy. Apparently, pleural empyema can lead to multi-organ involvement due to underlying inflammatory processes. This condition is usually associated with symptoms and changes in laboratory parameters that manifest after empyema treatment or reappear after temporary recovery. Hence, managing this condition by pulse corticosteroid therapy can result in positive outcomes.