Scholarlink

Background <p>This study aimed to determine the parameters that should be taken into consideration to predict the development of postoperative complications in patients aged 80 years and over (octogenarians) who underwent lung resection.</p> Methods <p>The data of 49 octogenarian patients who underwent lung resection between January 2016 and June 2025 were retrospectively analyzed. Patient demographics, operative parameters, and predictive indices and scores for postoperative complications (Charlson Comorbidity Index (CCI), Simplified Comorbidity Index (SCI), American Society of Anesthesiologists (ASA), Glasgow Prognostic Score (GPS), The Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) and Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM)) were calculated. Postoperative complications were recorded according to the Clavien-Dindo classification.</p> Results <p>The mean age of the patients, 79.6% of whom were male, was 81.98 ± 2.07 years. Statistically significantly fewer complications were observed in those who underwent sublobar resection compared to lobar resection (38.9% vs. 76.9%, <i>p</i> = 0.019). No correlation was found between CCI, SCI, ASA, and GPS scores and the development of complications (<i>p</i> = 0.170, <i>p</i> = 0.246, <i>p</i> = 0.774, <i>p</i> = 0.158, respectively), while ARISCAT and POSSUM scores were found to be predictive of complication development (<i>p</i> &lt; 0.001, <i>p</i> &lt; 0.001). In the multivariate analysis, while the extent of resection lost its status as an independent risk factor (<i>p</i> = 0.222), the classified ARISCAT score and the POSSUM score grouped according to the cut-off value determined by ROC analysis remained independent factors in predicting the development of complications. Patients in the high-risk group according to the ARISCAT score (OR = 16.482, 95% CI = 1.376-197.339, <i>p</i> = 0.027) and those with a POSSUM score above 31.100 (OR = 36.308, 95% CI = 3.889-338.952, <i>p</i> = 0.002) had a significantly higher incidence of postoperative complications.</p> Conclusions <p>In this single-centre study, higher ARISCAT and POSSUM scores were associated with the development of postoperative complications in octogenarians. Given the limited sample size, the wide confidence intervals, and the predominance of minor (Clavien–Dindo grade I–II) complications, these scores should be regarded as promising adjuncts for risk stratification that require validation in larger, prospective, multicentre studies before being applied to patient selection.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Can we predict postoperative complications in octogenarians undergoing lung resection?

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月30日

查看全文
  • Gizem Kececi Ozgur,
  • Hasan Yavuz,
  • Saltuk Burhan Dal,
  • Ahmet Kayahan Tekneci,
  • Ufuk Cagirici,
  • Tevfik Ilker Akcam,
  • Kutsal Turhan,
  • Ali Ozdil,
  • Ayse Gul Ergonul,
  • Alpaslan Cakan

摘要

Background

This study aimed to determine the parameters that should be taken into consideration to predict the development of postoperative complications in patients aged 80 years and over (octogenarians) who underwent lung resection.

Methods

The data of 49 octogenarian patients who underwent lung resection between January 2016 and June 2025 were retrospectively analyzed. Patient demographics, operative parameters, and predictive indices and scores for postoperative complications (Charlson Comorbidity Index (CCI), Simplified Comorbidity Index (SCI), American Society of Anesthesiologists (ASA), Glasgow Prognostic Score (GPS), The Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) and Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM)) were calculated. Postoperative complications were recorded according to the Clavien-Dindo classification.

Results

The mean age of the patients, 79.6% of whom were male, was 81.98 ± 2.07 years. Statistically significantly fewer complications were observed in those who underwent sublobar resection compared to lobar resection (38.9% vs. 76.9%, p = 0.019). No correlation was found between CCI, SCI, ASA, and GPS scores and the development of complications (p = 0.170, p = 0.246, p = 0.774, p = 0.158, respectively), while ARISCAT and POSSUM scores were found to be predictive of complication development (p < 0.001, p < 0.001). In the multivariate analysis, while the extent of resection lost its status as an independent risk factor (p = 0.222), the classified ARISCAT score and the POSSUM score grouped according to the cut-off value determined by ROC analysis remained independent factors in predicting the development of complications. Patients in the high-risk group according to the ARISCAT score (OR = 16.482, 95% CI = 1.376-197.339, p = 0.027) and those with a POSSUM score above 31.100 (OR = 36.308, 95% CI = 3.889-338.952, p = 0.002) had a significantly higher incidence of postoperative complications.

Conclusions

In this single-centre study, higher ARISCAT and POSSUM scores were associated with the development of postoperative complications in octogenarians. Given the limited sample size, the wide confidence intervals, and the predominance of minor (Clavien–Dindo grade I–II) complications, these scores should be regarded as promising adjuncts for risk stratification that require validation in larger, prospective, multicentre studies before being applied to patient selection.