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Objective <p>To evaluate the impact of ICU admission on mortality and complications of older patients with COVID-19 hospitalized during the first COVID-19 wave in our setting.</p> Methods <p>An observational, multicenter, and ambispective study of COVID-19 patients aged &gt; 70&#xa0;years who were hospitalized during the first wave of the pandemic in the southern metropolitan area of Barcelona, Spain. The primary outcome of the study was the in-hospital mortality rate of patients admitted to the ICU compared with their appropriately matched controls who received care in hospital wards. The secondary outcome was the in-hospital rate of complications in ICU-admitted patients versus their matched controls.</p> Results <p>The mortality rate was 76.6% in ICU-admitted patients and 64.9% among their matched controls, whereas the corresponding rates of complications were 73.5% and 32.4%, respectively. ICU admission shows a statistically significant impact on mortality (OR [95% CI] 2.50 [1.06–6.05]; <i>p</i> = 0.041). Additionally, complications were four times more likely in patients who were admitted to ICUs than in those admitted to general wards (OR [95% CI] 4.03 [1.64–9.91]; <i>p</i> = 0.0024).</p> Conclusions <p>ICU admission was not associated with improved survival in patients older than 70&#xa0;years during the first COVID-19 wave. Further research is needed to confirm these findings and to assess the adequacy of ICU admission criteria for elderly patients.</p> Trial registration <p>Not applicable.</p>

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Clinical effectiveness of intensive care unit admission in older adults with COVID-19 during the first pandemic wave in Spain

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月14日

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  • Marta Arroyo-Huidobro,
  • Carlos Pérez-López,
  • Natàlia Pallarès ,
  • Cristian Tebé Cordomí,
  • Antonella F. Simonetti,
  • Gabriela Abelenda-Alonso,
  • Alexander Rombauts,
  • Isabel Oriol Bermudez,
  • Elisenda Izquierdo,
  • Vicente Díaz-Brito,
  • Gemma Molist,
  • Guadalupe Gómez-Melis,
  • Sebastian Videla,
  • Alfons López Soto,
  • Jordi Carratalà,
  • Alejandro Rodríguez-Molinero,
  • Carlota Gudiol,
  • Judit Aranda-Lobo,
  • Montserrat Sanmartí,
  • Encarna Moreno,
  • Maria C. Alvarez,
  • Ana Faura,
  • Martha González,
  • Paula Cruz,
  • Mireia Colom,
  • Andrea Perez,
  • Laura Serrano,
  • Sebastià Videla,
  • Mireia Besalú,
  • Erik Cobo,
  • Jordi Cortés,
  • Daniel Fernández,
  • Leire Garmendia,
  • Guadalupe Gómez,
  • Pilar Hereu,
  • Klaus Langohr,
  • Núria Pérez-Álvarez,
  • Xavier Piulachs

摘要

Objective

To evaluate the impact of ICU admission on mortality and complications of older patients with COVID-19 hospitalized during the first COVID-19 wave in our setting.

Methods

An observational, multicenter, and ambispective study of COVID-19 patients aged > 70 years who were hospitalized during the first wave of the pandemic in the southern metropolitan area of Barcelona, Spain. The primary outcome of the study was the in-hospital mortality rate of patients admitted to the ICU compared with their appropriately matched controls who received care in hospital wards. The secondary outcome was the in-hospital rate of complications in ICU-admitted patients versus their matched controls.

Results

The mortality rate was 76.6% in ICU-admitted patients and 64.9% among their matched controls, whereas the corresponding rates of complications were 73.5% and 32.4%, respectively. ICU admission shows a statistically significant impact on mortality (OR [95% CI] 2.50 [1.06–6.05]; p = 0.041). Additionally, complications were four times more likely in patients who were admitted to ICUs than in those admitted to general wards (OR [95% CI] 4.03 [1.64–9.91]; p = 0.0024).

Conclusions

ICU admission was not associated with improved survival in patients older than 70 years during the first COVID-19 wave. Further research is needed to confirm these findings and to assess the adequacy of ICU admission criteria for elderly patients.

Trial registration

Not applicable.