Association and predictive value analysis for mobility assessments and concerns about falling on falls in community-dwelling older adults: a prospective cohort study in China
摘要
A series of mobility and concerns about falling measurement instruments are recommended by guidelines for fall prevention in older adults for fall risk assessment. However, evidence regarding their value in evaluating and predicting fall risk is inconsistent. This study aims to examine the associations and predictive ability between these assessments and falls in community-dwelling older adults in China.
MethodsMobility of 2544 participants aged
During the follow-up period, 236 (9.28%) participants reported at least one fall. Each standard deviation increase in TUG time was associated with a 1.154-fold greater risk of falls (95% CI: 1.035–1.286). Compared with participants with FES-I score ≤ 45, those with FES-I score > 45 had a 1.346-fold greater fall risk, with marginal statistical significance(95% CI: 0.995–1.822, P = 0.054). The ECUST and the 30s-CS were not associated with fall risk in the overall sample. Nonlinear relationship was not observed between mobility assessments and fall risk. And the non-linear correlation was marginally significant between FES-I and fall risk (P = 0.056). The predictive accuracy of the TUG and FES-I used in isolation or in combination was poor, with C statistics ranging from 0.545 to 0.568. The predictive performance was significantly enhanced but still insufficient after baseline characteristics were incorporated into the model, with a C-statistic of 0.631 (95% CI: 0.594–0.667), an IDI of 0.013 (95% CI: 0.010–0.040) and a NRI of 0.178 (95% CI: 0.111–0.260).
ConclusionThe TUG test is an useful tool for evaluating fall risk in community-dwelling older adults. The FES-I has potential to identify older adults at an elevated risk of fall with a cut-off value of 45. However, their ability to predict falls is limited. Incorporating additional fall-related factors improves the predictive performance but is still inadequate.