Prevalence and risk factors of metabolic dysfunction-associated fatty liver disease in the adult Georgian population: a nationwide multiregional clinic-based study
摘要
In Georgia, the prevalence of MAFLD remains poorly defined, as evidence largely stems from small-scale hospital studies. This research used a nationwide multiregional clinic-based sample to estimate MAFLD prevalence and its associated factors.
MethodsA cross-sectional, clinic-based study was conducted on 11,269 adults attending check-up clinics across Georgia from 2021 to 2025. A stratified random sampling approach considering age, sex, BMI, comorbidities and region was used to derive a representative analytic sample (n = 5,602). MAFLD was diagnosed using ultrasound and international consensus positive diagnostic criteria.
ResultsMAFLD affected 51.6% of Georgian adults, with higher prevalence in older age, men and individuals with obesity or metabolic comorbidities. Prevalence varied significantly across regions, with the highest in Tbilisi.
ConclusionMAFLD is highly prevalent in Georgia. Due to the clinic-based nature of the sample, results should be interpreted with consideration of potential selection bias.