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Background <p>In the emergency department, chest pain is a common presentation, and the primary clinical challenge is the early identification of patients at risk of major adverse cardiac events (MACE). This study aimed to evaluate the diagnostic performance of the SVEAT (Symptoms, Vascular Disease History, ECG, Age, and Troponin) score in predicting 90-day MACE in patients presenting with acute chest pain.</p> Methods <p>This study included 348 patients presenting with acute chest pain. Serial high-sensitivity troponin I (HsTn-I) measurements were obtained at admission and 2&#xa0;h later. Electrocardiographic and clinical data were recorded, and the SVEAT, HEART, and TIMI scores were calculated. Patients were followed for 90 days for MACE occurrence.</p> Results <p>MACE occurred in 7.2% of patients during the 90-day follow-up. The second high-sensitivity troponin I (HsTn-I) measurement was significantly associated with MACE (<i>p</i> = 0.007). The SVEAT score demonstrated the highest discriminative performance (AUC = 0.806), compared with the HEART score (AUC = 0.756) and TIMI score (AUC = 0.753). At the optimal cut-off value of 4, the SVEAT score showed a sensitivity of 0.56 and a specificity of 0.86. In comparison, both the HEART and TIMI scores (cut-off = 3) showed higher sensitivity (0.72), with specificity values of 0.72 and 0.63, respectively.</p> Clinical trial number <p>Not applicable.</p> Conclusion <p>The SVEAT score may have potential as a rule-in tool for predicting 90-day MACE in emergency department patients presenting with acute chest pain, due to its higher specificity; however, this is accompanied by relatively low sensitivity, which limits its utility as a standalone screening tool.</p>

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Performance of the SVEAT (Symptoms, Vascular Disease History, Electrocardiography, Age, and Troponin) score for predicting 90-day major adverse cardiac events in patients with acute chest pain

  • 期刊论文

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  • 发表日期：

    2026年7月16日

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  • Ali Ayvaz,
  • Akkan Avci,
  • Mustafa Oguz Tugcan,
  • Muhammed Mert Can,
  • Ahmet Burak Urfalioglu,
  • Erdem Aksay,
  • Yeliz Simsek,
  • Sadiye Yolcu Seven,
  • Begum Seyda Avci,
  • Ecem Basak Kaya,
  • Aysegul Sancaktar,
  • Mehmet Bankir,
  • Ramazan Guven

摘要

Background

In the emergency department, chest pain is a common presentation, and the primary clinical challenge is the early identification of patients at risk of major adverse cardiac events (MACE). This study aimed to evaluate the diagnostic performance of the SVEAT (Symptoms, Vascular Disease History, ECG, Age, and Troponin) score in predicting 90-day MACE in patients presenting with acute chest pain.

Methods

This study included 348 patients presenting with acute chest pain. Serial high-sensitivity troponin I (HsTn-I) measurements were obtained at admission and 2 h later. Electrocardiographic and clinical data were recorded, and the SVEAT, HEART, and TIMI scores were calculated. Patients were followed for 90 days for MACE occurrence.

Results

MACE occurred in 7.2% of patients during the 90-day follow-up. The second high-sensitivity troponin I (HsTn-I) measurement was significantly associated with MACE (p = 0.007). The SVEAT score demonstrated the highest discriminative performance (AUC = 0.806), compared with the HEART score (AUC = 0.756) and TIMI score (AUC = 0.753). At the optimal cut-off value of 4, the SVEAT score showed a sensitivity of 0.56 and a specificity of 0.86. In comparison, both the HEART and TIMI scores (cut-off = 3) showed higher sensitivity (0.72), with specificity values of 0.72 and 0.63, respectively.

Clinical trial number

Not applicable.

Conclusion

The SVEAT score may have potential as a rule-in tool for predicting 90-day MACE in emergency department patients presenting with acute chest pain, due to its higher specificity; however, this is accompanied by relatively low sensitivity, which limits its utility as a standalone screening tool.