Objective <p>To explore the clinical characteristics and influencing factors of patients with chronic heart failure (CHF) complicated with hypertension.</p> Methods <p>CHF patients hospitalized in our hospital from June 2022 to January 2024 included 120 patients with hypertension (hypertension group) and 120 patients without hypertension (no hypertension group). The clinical characteristics and risk factors were analyzed by univariate analysis and multi-factor logistic regression model.</p> Results <p>The results of univariate analysis showed that age, course of CHF, complicated with diabetes, left ventricular ejection fraction (LVEF), 6-minute walking distance, New York Heart Association (NYHA) cardiac function classification, systolic blood pressure (SBP), DBP(diastolic blood pressure), peripheral blood hemoglobin (Hb), serum creatinine(Scr), blood urea nitrogen (BUN), The differences in uric acid and glycosylated hemoglobin A1c (HbA1c) levels between the hypertension group and the non-hypertension group were statistically significant (all <i>p</i> &lt; 0.05). Further multi-factor logistic regression analysis showed that age, NYHA cardiac function classification, complicated with diabetes, LVEF, peripheral blood Hb and HbA1c levels are independent influencing factors of CHF combined with hypertension (all <i>p</i> &lt; 0.05), among which LVEF and peripheral blood. A lower Hb level was associated with a higher risk of hypertension, indicating that a higher Hb level is an independent protective factor against hypertension in patients with CHF; while the higher the age, NYHA cardiac function classification, complicated with diabetes and HbA1c level, the higher the risk of hypertension.</p> Conclusion <p>Age, NYHA cardiac function classification, complicated with diabetes, LVEF, peripheral blood Hb and HbA1c levels are all independent influencing factors of CHF combined with hypertension.</p>