Scholarlink

Background <p>Cardiovascular morbidity is still an epidemiological problem, especially related to the risk of re-intervention. In addition to classical atherosclerosis risk factors, the influence of climate changes related to ambient temperature exposure has been recently taken into account. The individual approach is indicated as desirable and justified for clinical conclusion drawing. The possible relation between air temperature and coronary artery atherosclerosis progression was the subject of our study.</p> Methods <p>Out of 224 patients, 146 (100 (68%) males and 46 (32%) females in a mean (standard devation – SD) age of 67.7 ± 7.7&#xa0;years) underwent percutaneous coronary intervention (PCI) followed by repeated angiography due to angina equivalent symptoms after median (Q1-3) 510 (154—1451) days. Demographical, clinical, and angiographical characteristics, followed by ambient temperature exposure within the time interval between both angiographic evaluations, were interpreted for predictors of coronary artery stenosis progression.</p> Results <p>In the multivariable analysis, mean yearly ambient temperatures (<i>p</i> = 0.018), exposure to extreme low (below – 10 <sup>0</sup>C) (<i>p</i> = 0.032), and warm (above 25 <sup>0</sup>C) temperatures (<i>p</i> = 0.023), were found predictive for stenosis progression.</p> Conclusions <p>The coronary disease progression was found to be age-related and modulated by ambient temperature exposures. The low ambient temperatures in patients with previous percutaneous interventions may relate to premature significant coronary culprit lesion progression. The exposure to days characterized by warm temperatures may be regarded as protective. The climatic changes represented by mean yearly temperature growth can be regarded as an ominous factor for plaque progression.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Low air-temperatures exposure as a risk factor for coronary artery disease progression – personalized analysis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月29日

查看全文
  • Tomasz Urbanowicz,
  • Krzysztof Skotak,
  • Anna Olasińska-Wiśniewska,
  • Krzysztof J. Filipiak,
  • Jakub Bratkowski,
  • Krystian Szczepański,
  • Michał Wyrwa,
  • Kajetan Grodecki,
  • Jędrzej Sikora,
  • Marta Krama,
  • Beata Krasińska,
  • Zbigniew Krasiński,
  • Andrzej Tykarski,
  • Marek Jemielity

摘要

Background

Cardiovascular morbidity is still an epidemiological problem, especially related to the risk of re-intervention. In addition to classical atherosclerosis risk factors, the influence of climate changes related to ambient temperature exposure has been recently taken into account. The individual approach is indicated as desirable and justified for clinical conclusion drawing. The possible relation between air temperature and coronary artery atherosclerosis progression was the subject of our study.

Methods

Out of 224 patients, 146 (100 (68%) males and 46 (32%) females in a mean (standard devation – SD) age of 67.7 ± 7.7 years) underwent percutaneous coronary intervention (PCI) followed by repeated angiography due to angina equivalent symptoms after median (Q1-3) 510 (154—1451) days. Demographical, clinical, and angiographical characteristics, followed by ambient temperature exposure within the time interval between both angiographic evaluations, were interpreted for predictors of coronary artery stenosis progression.

Results

In the multivariable analysis, mean yearly ambient temperatures (p = 0.018), exposure to extreme low (below – 10 0C) (p = 0.032), and warm (above 25 0C) temperatures (p = 0.023), were found predictive for stenosis progression.

Conclusions

The coronary disease progression was found to be age-related and modulated by ambient temperature exposures. The low ambient temperatures in patients with previous percutaneous interventions may relate to premature significant coronary culprit lesion progression. The exposure to days characterized by warm temperatures may be regarded as protective. The climatic changes represented by mean yearly temperature growth can be regarded as an ominous factor for plaque progression.