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Objective <p>To evaluate the diagnostic utility of penile colour Doppler ultrasonography (CDU) in characterizing the vascular etiology of erectile dysfunction (ED) in a Ugandan population.</p> Methods <p>A retrospective analysis was conducted on 51 patients with non-neurological, non-metabolic ED at a tertiary institution. All patients underwent standardized penile CDU after intracavernosal injection of 20&#xa0;µg Prostaglandin E1 (PGE1), with assessment of peak systolic velocity (PSV), end-diastolic velocity (EDV), and cavernosal artery diameter.</p> Results <p>The mean age was 48.65 years. Arterial insufficiency was the most common finding (45.1% of cases), with 78.26% of these being bilateral. Mixed arterial-venous dysfunction was identified in 35.29% of patients, while isolated venous leakage was rare (3.92%). Only 13.73% of studies were normal. A key finding was the disparity between structural and functional assessments: while B-mode ultrasound appeared normal in 74.51% of cases, Doppler revealed vascular abnormalities in the vast majority.</p> Conclusion <p>Penile CDU is a valuable non-invasive tool for detecting vasculogenic ED in this setting, with arterial insufficiency being the predominant etiology. The frequent discrepancy between normal B-mode anatomy and abnormal hemodynamics highlights the essential role of doppler velocimetry in diagnosis.</p>

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The Arterial Deficit: Characterizing Erectile Dysfunction with Penile Colour Doppler in a Ugandan Population.

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月21日

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  • Ampuriire Nyakubaho,
  • Henry Sematimba,
  • Melodie Munyakazi,
  • Victoria Nakalanzi,
  • Frank Ssebaggala,
  • Michael Kawooya G

摘要

Objective

To evaluate the diagnostic utility of penile colour Doppler ultrasonography (CDU) in characterizing the vascular etiology of erectile dysfunction (ED) in a Ugandan population.

Methods

A retrospective analysis was conducted on 51 patients with non-neurological, non-metabolic ED at a tertiary institution. All patients underwent standardized penile CDU after intracavernosal injection of 20 µg Prostaglandin E1 (PGE1), with assessment of peak systolic velocity (PSV), end-diastolic velocity (EDV), and cavernosal artery diameter.

Results

The mean age was 48.65 years. Arterial insufficiency was the most common finding (45.1% of cases), with 78.26% of these being bilateral. Mixed arterial-venous dysfunction was identified in 35.29% of patients, while isolated venous leakage was rare (3.92%). Only 13.73% of studies were normal. A key finding was the disparity between structural and functional assessments: while B-mode ultrasound appeared normal in 74.51% of cases, Doppler revealed vascular abnormalities in the vast majority.

Conclusion

Penile CDU is a valuable non-invasive tool for detecting vasculogenic ED in this setting, with arterial insufficiency being the predominant etiology. The frequent discrepancy between normal B-mode anatomy and abnormal hemodynamics highlights the essential role of doppler velocimetry in diagnosis.