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Background <p>Spontaneous bladder rupture is a rare condition typically presenting with abdominal pain and peritonitis. Although bladder malignancies seldom cause spontaneous perforation, when they do, the condition carries a high mortality rate due to delayed diagnosis and poor prognosis.</p> Case presentation <p>A 69-year-old woman with a history of subtotal hysterectomy presented with acute abdominal pain and recurrent hematuria. Imaging showed a bladder rupture. Extensive bladder necrosis and multiple perforations were found during surgery, necessitating cystectomy. Histopathology confirmed infiltrating keratinizing squamous cell carcinoma (SCC). Her condition deteriorated postoperatively, and she died 4&#xa0;months later.</p> Conclusions <p>This case highlights the diagnostic and therapeutic challenges of spontaneous bladder rupture in SCC, the aggressive nature of the malignancies causing spontaneous bladder rupture, and the need for high clinical suspicion and timely intervention.</p>

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Squamous cell carcinoma of the bladder as a cause of spontaneous bladder rupture: a case report

  • 期刊论文

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  • 发表日期：

    2025年3月10日

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  • Reda Tariqi,
  • Hamza El Abidi,
  • Ismail Boujida,
  • Sabrine Darqaoui,
  • Imad Boualaoui,
  • Ahmed Ibrahimi,
  • Hachem El Sayegh,
  • Yassine Nouini

摘要

Background

Spontaneous bladder rupture is a rare condition typically presenting with abdominal pain and peritonitis. Although bladder malignancies seldom cause spontaneous perforation, when they do, the condition carries a high mortality rate due to delayed diagnosis and poor prognosis.

Case presentation

A 69-year-old woman with a history of subtotal hysterectomy presented with acute abdominal pain and recurrent hematuria. Imaging showed a bladder rupture. Extensive bladder necrosis and multiple perforations were found during surgery, necessitating cystectomy. Histopathology confirmed infiltrating keratinizing squamous cell carcinoma (SCC). Her condition deteriorated postoperatively, and she died 4 months later.

Conclusions

This case highlights the diagnostic and therapeutic challenges of spontaneous bladder rupture in SCC, the aggressive nature of the malignancies causing spontaneous bladder rupture, and the need for high clinical suspicion and timely intervention.