Scholarlink

Background <p>Scombroid syndrome, a pseudo-allergic reaction caused by histamine-contaminated fish, is often mistaken for type I hypersensitivity reactions due to overlapping clinical presentations. Unlike IgE-mediated anaphylaxis, Scombroid syndrome results from histamine production by bacterial histidine decarboxylase in improperly preserved fish. It accounts for 5% of U.S. food poisoning cases and manifests within 30&#xa0;min to two hours post-ingestion.</p> Case presentation <p>Symptoms include rash, pruritus, vomiting, and tongue swelling, as exemplified by a case of a 30-year-old woman misdiagnosed with anaphylaxis after consuming salmon. However, typically mild and self-limiting, severe cases may involve bronchospasm and arrhythmias. Diagnosis hinges on patient history, symptom onset, and absence of food allergy markers, such as elevated tryptase. Management includes antihistamines and supportive care; epinephrine and corticosteroids are reserved for severe reactions.</p> Conclusion <p>Clinicians must distinguish Scombroid syndrome from anaphylaxis to ensure accurate treatment, emphasizing proper fish preservation to prevent outbreaks.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Case of scombroid syndrome mimicking an anaphylactic fish allergy

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月3日

查看全文
  • Véronique Gingras,
  • Louis Marois

摘要

Background

Scombroid syndrome, a pseudo-allergic reaction caused by histamine-contaminated fish, is often mistaken for type I hypersensitivity reactions due to overlapping clinical presentations. Unlike IgE-mediated anaphylaxis, Scombroid syndrome results from histamine production by bacterial histidine decarboxylase in improperly preserved fish. It accounts for 5% of U.S. food poisoning cases and manifests within 30 min to two hours post-ingestion.

Case presentation

Symptoms include rash, pruritus, vomiting, and tongue swelling, as exemplified by a case of a 30-year-old woman misdiagnosed with anaphylaxis after consuming salmon. However, typically mild and self-limiting, severe cases may involve bronchospasm and arrhythmias. Diagnosis hinges on patient history, symptom onset, and absence of food allergy markers, such as elevated tryptase. Management includes antihistamines and supportive care; epinephrine and corticosteroids are reserved for severe reactions.

Conclusion

Clinicians must distinguish Scombroid syndrome from anaphylaxis to ensure accurate treatment, emphasizing proper fish preservation to prevent outbreaks.