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Background <p>Chronic subdural hematoma (CSDH) is a common condition in elderly patients, typically diagnosed through neuroimaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI). Cases of subdural lymphoma mimicking chronic subdural hematoma are exceedingly rare and present significant diagnostic challenges for emergency physicians.</p> Case presentation <p>A 71-year-old female patient with subdural lymphoma was initially diagnosed with CSDH based on her medical history, clinical presentation, and neuroimaging findings. However, postoperative pathology revealed diffuse subdural lymphoma. Although the patient’s symptoms initially improved following standard lymphoma treatment, the disease recurred within 14 months of follow-up. The patient ultimately succumbed to malignant intracranial hypertension 15 months after discharge.</p> Conclusions <p>This article discusses the neuroimaging findings, histological features, and treatment strategies of this case, while reviewing the limited number of similar cases reported since 2000. Based on the diagnostic and therapeutic experience of this case, it is recommended that when a patient’s clinical presentation deviates from that of typical chronic subdural hematoma, supplementary MRI with diffusion-weighted imaging (DWI) should be considered to aid in differential diagnosis.</p>

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Primary subdural lymphoma mimicking chronic subdural hematoma: a case report and a narrative review of some recent similar cases in the literature

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月25日

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  • Yibo Han,
  • Bin Chen,
  • Meiyu Zeng,
  • Dong Liang,
  • Yibao Wang,
  • Yong Wang

摘要

Background

Chronic subdural hematoma (CSDH) is a common condition in elderly patients, typically diagnosed through neuroimaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI). Cases of subdural lymphoma mimicking chronic subdural hematoma are exceedingly rare and present significant diagnostic challenges for emergency physicians.

Case presentation

A 71-year-old female patient with subdural lymphoma was initially diagnosed with CSDH based on her medical history, clinical presentation, and neuroimaging findings. However, postoperative pathology revealed diffuse subdural lymphoma. Although the patient’s symptoms initially improved following standard lymphoma treatment, the disease recurred within 14 months of follow-up. The patient ultimately succumbed to malignant intracranial hypertension 15 months after discharge.

Conclusions

This article discusses the neuroimaging findings, histological features, and treatment strategies of this case, while reviewing the limited number of similar cases reported since 2000. Based on the diagnostic and therapeutic experience of this case, it is recommended that when a patient’s clinical presentation deviates from that of typical chronic subdural hematoma, supplementary MRI with diffusion-weighted imaging (DWI) should be considered to aid in differential diagnosis.