Scholarlink

<p>This study explores the green synthesis of gold nanoparticles (AuNPs) using the aqueous extract of <i>Boerhavia diffusa</i> L., a plant known for its medicinal properties. The synthesis of AuNPs was confirmed through UV–Vis spectroscopy, showing a characteristic surface plasmon resonance peak at 551 nm, indicating successful nanoparticle (NPs) formation. The physicochemical properties of the NPs were further analyzed using FTIR, XRD, SEM, and DLS, revealing a crystalline structure, spherical morphology, and an average size of 53.17 ± 0.58 nm. The biogenic AuNPs were evaluated for their antimicrobial, antifungal, antioxidant, and anticancer activities. AuNPs exhibited significant antibacterial effects against <i>Listeria monocytogenes</i>, <i>Bordetella bronchiseptica</i>, and <i>Escherichia coli</i>, with zone of inhibition ranging from 25 to 27 mm. In antifungal assays, AuNPs displayed potent activity against <i>Candida albicans</i>, <i>Aspergillus niger</i>, <i>Cryptococcus neoformans</i>, and <i>Trichophyton rubrum</i>, with inhibition zones between 78 and 86 mm. The antioxidant potential was also demonstrated through DPPH, FRAP, and TPC assays, with AuNPs showing ~ 80% radical scavenging activity. Furthermore, cytotoxicity analysis revealed that AuNPs reduced the viability of HepG2 cancer cells by approximately 39% at 100 µg/mL. These findings highlight the potential of BD@AuNPs as multifunctional nanomaterials for biomedical applications, offering eco-friendly and sustainable alternatives for drug delivery and therapy.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Phytosynthesis of gold nanoparticles from Boerhavia diffusa L. and their antibacterial, antifungal, antioxidant, and anticancer activities

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月9日

查看全文
  • Yasmeen Bibi,
  • Zahida Nasreen,
  • Hansa Gul,
  • Nasir Assad,
  • Muhammad Nauman Khan,
  • Dawit Kifle,
  • Muhammad Naeem-Ul-Hassan,
  • Sezai Ercişli

摘要

This study explores the green synthesis of gold nanoparticles (AuNPs) using the aqueous extract of Boerhavia diffusa L., a plant known for its medicinal properties. The synthesis of AuNPs was confirmed through UV–Vis spectroscopy, showing a characteristic surface plasmon resonance peak at 551 nm, indicating successful nanoparticle (NPs) formation. The physicochemical properties of the NPs were further analyzed using FTIR, XRD, SEM, and DLS, revealing a crystalline structure, spherical morphology, and an average size of 53.17 ± 0.58 nm. The biogenic AuNPs were evaluated for their antimicrobial, antifungal, antioxidant, and anticancer activities. AuNPs exhibited significant antibacterial effects against Listeria monocytogenes, Bordetella bronchiseptica, and Escherichia coli, with zone of inhibition ranging from 25 to 27 mm. In antifungal assays, AuNPs displayed potent activity against Candida albicans, Aspergillus niger, Cryptococcus neoformans, and Trichophyton rubrum, with inhibition zones between 78 and 86 mm. The antioxidant potential was also demonstrated through DPPH, FRAP, and TPC assays, with AuNPs showing ~ 80% radical scavenging activity. Furthermore, cytotoxicity analysis revealed that AuNPs reduced the viability of HepG2 cancer cells by approximately 39% at 100 µg/mL. These findings highlight the potential of BD@AuNPs as multifunctional nanomaterials for biomedical applications, offering eco-friendly and sustainable alternatives for drug delivery and therapy.