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<p>This article explores the phyto-synthesis of silver nanoparticles (Ag&#xa0;NPs) derived from the floral extract of <i>Punica granatum</i> and their potential applications in antibacterial and anticancer treatments. In the synthesis process, silver nitrate (AgNO<sub>3</sub>) has been utilized as both a reducing and stabilizing agent, leading to the successful formation of stable silver nanoparticles (PG-Ag NPs). The nanoparticles were characterized using various analytical techniques, revealing their spherical shape and uniform dispersion, with an average size of ~ 27 (± 2) nm. The antibacterial and anticancer properties of the PG-AgNPs have been investigated, demonstrating significant anticancer activity with an IC<sub>50</sub> value of ~ 13&#xa0;µg/mL. Furthermore, the nanoparticles exhibited potent antimicrobial efficacy against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>. These findings indicate that PG-Ag NPs, synthesized from <i>Punica granatum</i> flower extract, present a promising and cost-effective solution for antibacterial and anticancer applications.</p>

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A novel approach for phyto-synthesis of silver nanoparticles using floral extract of Punica granatum for potent anti-cancerous and antibacterial capabilities

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月16日

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  • Sumit K. Shrivastava,
  • Asita Kulshreshtha,
  • Rajesh K. Gangwar,
  • Shikha Srivastava,
  • Monisha Banerjee,
  • Saurabh Kumar,
  • Shama Parveen,
  • Dhirendra K. Chaudhary,
  • Dimple Kumari,
  • Abhishek P. Tiwari

摘要

This article explores the phyto-synthesis of silver nanoparticles (Ag NPs) derived from the floral extract of Punica granatum and their potential applications in antibacterial and anticancer treatments. In the synthesis process, silver nitrate (AgNO3) has been utilized as both a reducing and stabilizing agent, leading to the successful formation of stable silver nanoparticles (PG-Ag NPs). The nanoparticles were characterized using various analytical techniques, revealing their spherical shape and uniform dispersion, with an average size of ~ 27 (± 2) nm. The antibacterial and anticancer properties of the PG-AgNPs have been investigated, demonstrating significant anticancer activity with an IC50 value of ~ 13 µg/mL. Furthermore, the nanoparticles exhibited potent antimicrobial efficacy against Escherichia coli and Staphylococcus aureus. These findings indicate that PG-Ag NPs, synthesized from Punica granatum flower extract, present a promising and cost-effective solution for antibacterial and anticancer applications.