Scholarlink

Background <p>Primary headache disorders, particularly migraine, are closely linked to sleep disturbances. However, the relationship between headache phenotypes, sleep quality, and chronotype in large populations remains to be fully elucidated. This study aimed to investigate sleep quality and chronotype across different primary headache types compared to headache-free individuals.</p> Methods <p>This nationwide, cross-sectional study included 5,311 Polish adults recruited via an online research panel. Headaches were classified using the HARDSHIP questionnaire according to ICHD-3 criteria. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and chronotype using the Morningness-Eveningness Questionnaire (MEQ). Sleep-related variables were then compared between specific headache types and individuals without headache.</p> Results <p>Participants with migraine (<i>n</i> = 1,523) reported the poorest sleep quality (median PSQI: 7 vs. 5 in controls) and the highest prevalence of poor sleep (64.1% vs. 38.7% in controls; <i>p</i> &lt; 0.001). After adjustment, migraine (β = 2.09), unclassified headache (β = 1.57), and tension-type headache (TTH; β = 0.59) remained significantly associated with higher PSQI scores. Regarding chronotype, the migraine group showed a significant shift toward eveningness (adjusted β=-1.38; <i>p</i> &lt; 0.001) and a lower representation of morning types (24.9% vs. 39.1% in controls). In the migraine subgroup, poorer sleep quality was moderately correlated with lower quality of life (<i>r</i>=-0.45) and higher perceived stress (<i>r</i> = 0.34), whereas MEQ scores showed only weak correlations with clinical outcomes.</p> Conclusions <p>Poor sleep quality and an evening chronotype are prominent features of primary headache disorders, especially migraine. Future prospective studies are needed to determine the causality of these associations. Meanwhile, sleep quality assessment and interventions aiming to improve sleep patterns should be considered in migraine patients.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Sleep quality and chronotype in primary headache disorders: a nationwide population-based study of 5,311 Polish adults

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月19日

查看全文
  • Karol Marschollek,
  • Helena Martynowicz,
  • Sławomir Budrewicz,
  • Marcin Straburzyński,
  • Marta Waliszewska-Prosół

摘要

Background

Primary headache disorders, particularly migraine, are closely linked to sleep disturbances. However, the relationship between headache phenotypes, sleep quality, and chronotype in large populations remains to be fully elucidated. This study aimed to investigate sleep quality and chronotype across different primary headache types compared to headache-free individuals.

Methods

This nationwide, cross-sectional study included 5,311 Polish adults recruited via an online research panel. Headaches were classified using the HARDSHIP questionnaire according to ICHD-3 criteria. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and chronotype using the Morningness-Eveningness Questionnaire (MEQ). Sleep-related variables were then compared between specific headache types and individuals without headache.

Results

Participants with migraine (n = 1,523) reported the poorest sleep quality (median PSQI: 7 vs. 5 in controls) and the highest prevalence of poor sleep (64.1% vs. 38.7% in controls; p < 0.001). After adjustment, migraine (β = 2.09), unclassified headache (β = 1.57), and tension-type headache (TTH; β = 0.59) remained significantly associated with higher PSQI scores. Regarding chronotype, the migraine group showed a significant shift toward eveningness (adjusted β=-1.38; p < 0.001) and a lower representation of morning types (24.9% vs. 39.1% in controls). In the migraine subgroup, poorer sleep quality was moderately correlated with lower quality of life (r=-0.45) and higher perceived stress (r = 0.34), whereas MEQ scores showed only weak correlations with clinical outcomes.

Conclusions

Poor sleep quality and an evening chronotype are prominent features of primary headache disorders, especially migraine. Future prospective studies are needed to determine the causality of these associations. Meanwhile, sleep quality assessment and interventions aiming to improve sleep patterns should be considered in migraine patients.