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Abstract <p><i>Pleurotus eryngii</i> (King Oyster Mushroom) is a nutritionally rich and pharmacologically potent edible fungus, containing high-quality proteins, vitamins, minerals, and diverse bioactive compounds such as polysaccharides, phenolics, terpenoids, and lovastatin-like molecules. These components contribute to a broad spectrum of biological effects, including antioxidant, anti-inflammatory, antitumor, antidiabetic, hypolipidemic, hepatoprotective, neuroprotective, and antimicrobial activities. The mushroom’s bioactive compounds act through modulation of oxidative stress, immune responses, and metabolic pathways, highlighting its therapeutic relevance in managing chronic and degenerative diseases. Moreover, its ease of cultivation and environmental sustainability enhance its potential as a functional food and natural health-promoting agent. Future research should emphasize clinical validation, molecular mechanism elucidation, and biotechnological enhancement for pharmaceutical and nutraceutical development.</p>

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Integrative Review of the Nutritional Composition, Phytochemical Profile, and Therapeutic Potential of Pleurotus eryngii

  • 期刊论文

  • 发表日期：

    2026年4月13日

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  • Umer Rehman,
  • Mohsin Ullah,
  • Muhammad Asif,
  • Atika Noor,
  • Fahim Ullah,
  • Zabta Khan Shinwari

摘要

Abstract

Pleurotus eryngii (King Oyster Mushroom) is a nutritionally rich and pharmacologically potent edible fungus, containing high-quality proteins, vitamins, minerals, and diverse bioactive compounds such as polysaccharides, phenolics, terpenoids, and lovastatin-like molecules. These components contribute to a broad spectrum of biological effects, including antioxidant, anti-inflammatory, antitumor, antidiabetic, hypolipidemic, hepatoprotective, neuroprotective, and antimicrobial activities. The mushroom’s bioactive compounds act through modulation of oxidative stress, immune responses, and metabolic pathways, highlighting its therapeutic relevance in managing chronic and degenerative diseases. Moreover, its ease of cultivation and environmental sustainability enhance its potential as a functional food and natural health-promoting agent. Future research should emphasize clinical validation, molecular mechanism elucidation, and biotechnological enhancement for pharmaceutical and nutraceutical development.