Abstract <p>One approach to reduce “white pollution” can be to identify potential algae and cyanobacteria, and the metabolic products they produce that can successfully break down polymeric materials biologically. By generating ligninolytic and exopolysaccharide enzymes that break down the chemical bonds of plastic polymers, microalgae contribute to the biodegradation of waste plastic. It is quite intriguing to try and use microalgae to break these polymers down into metabolites like carbon dioxide, water, and new biomass. In spite of this, more study is required because this is a novel field of research. More research on this subject is required, including an examination of the presence of enzymes and their role in the biodegradation of polymers. Hence this review has been focused on studies reporting different enzymes in microalgae, various enzymes mainly associated with biodegradation and their occurrences in microalgae. The described enzymes included laccases, manganese peroxidase, lignin peroxidase, cellulases, amylases, galactosidases, proteases, lipases, phytases, and superoxide dismutase enzymes that involved in biodegradation.</p>