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Abstract <p>Neurofilament Light Chain (NfL), as a sensitive biomarker of neuronal axonal injury, holds significant value in the diagnosis, prognosis assessment, and treatment of Traumatic Brain Injury (TBI). This study integrates data from bioinformatics, basic experiments, and clinical research to systematically analyze the multi-dimensional role of NfL in TBI. NfL has important biological and clinical significance in TBI. As a sensitive biomarker of neural injury, it provides new research directions for the early diagnosis, prognosis assessment, and treatment of TBI.</p>

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Multi-Angle Analysis of Neurofilament Light Chain in Traumatic Brain Injury

  • 期刊论文

  • 发表日期：

    2026年7月19日

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  • Gengshui Zhao,
  • Pengpeng Kang,
  • Dongqian Wu,
  • Xiaocui Zhu

摘要

Abstract

Neurofilament Light Chain (NfL), as a sensitive biomarker of neuronal axonal injury, holds significant value in the diagnosis, prognosis assessment, and treatment of Traumatic Brain Injury (TBI). This study integrates data from bioinformatics, basic experiments, and clinical research to systematically analyze the multi-dimensional role of NfL in TBI. NfL has important biological and clinical significance in TBI. As a sensitive biomarker of neural injury, it provides new research directions for the early diagnosis, prognosis assessment, and treatment of TBI.