Scholarlink

<p>Immune dysregulation and inflammation play a key role in the pathogenesis of various affective disorders associated with excessive aggressiveness. Aggressive behavior formed in experimental models under the influence of psychological stress or genetic factors is accompanied by changes in immune function, production of circulating cytokines, as well as temporal and region-dependent variations in their content within brain structures involved in behavior control and immunomodulation. Studying a role of neuroimmune interactions in the regulation of aggressive behavior is a fundamental challenge not only to advance our understanding of the neurobiological mechanisms underlying human aggression and violence, but also to develop effective approaches to its correction.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Neuroimmune Disturbances in Animal Models of Aggressive Behavior

  • 期刊论文

  • 发表日期：

    2025年9月1日

查看全文
  • E. L. Alperina,
  • S. Ya. Zhanaeva,
  • G. V. Idova

摘要

Immune dysregulation and inflammation play a key role in the pathogenesis of various affective disorders associated with excessive aggressiveness. Aggressive behavior formed in experimental models under the influence of psychological stress or genetic factors is accompanied by changes in immune function, production of circulating cytokines, as well as temporal and region-dependent variations in their content within brain structures involved in behavior control and immunomodulation. Studying a role of neuroimmune interactions in the regulation of aggressive behavior is a fundamental challenge not only to advance our understanding of the neurobiological mechanisms underlying human aggression and violence, but also to develop effective approaches to its correction.