Abstract <p>Numerical simulation of a dispersed phase scattering in a turbulent droplet-laden flow in a cylindrical channel with a peripheral swirling has been performed with variations in the initial weight concentration of water droplets within the range <i>M</i>_<i>L</i>1 = 0−0.1 and the initial droplet diameter <i>d</i>₁ = 10–100 µm using Eulerian and Lagrangian descriptions. The gas phase is described by a system of three-dimensional URANS equations, taking into account the effect of particles on transport processes in the carrier phase. The turbulence of the gas phase is calculated using the elliptical Reynolds stress transfer model, taking into account the effect of the dispersed phase. The Eulerian and Lagrangian descriptions give qualitatively similar computation results for the mass concentration profiles of droplets over the entire studied range of their initial diameters and concentrations (the difference in the computation results does not exceed 20%) and the position of the local concentration maximum. Comparisons have been made with the data of LES computations and measurements of the swirling droplet-laden flow at the swirl number <i>S</i> = 0.7, for which the precession of the vortex core occurs.</p>