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Abstract <p>The high efficiency of Michael addition of amines to β-fluoro-β-nitrostyrenes has been demonstrated for wide ranges of primary amines and nitrostyrenes. The reaction smoothly proceeds at room temperature without a catalyst. A number of new fluorine-containing Michael adducts have been synthesized in up to quantitative yield.</p>

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Aza-Michael Reaction of β-Fluoro-β-nitrostyrenes

  • 期刊论文

  • 发表日期：

    2026年3月1日

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  • A. S. Aldoshin,
  • J. Zhang,
  • V. E. Shambalova,
  • V. G. Nenajdenko

摘要

Abstract

The high efficiency of Michael addition of amines to β-fluoro-β-nitrostyrenes has been demonstrated for wide ranges of primary amines and nitrostyrenes. The reaction smoothly proceeds at room temperature without a catalyst. A number of new fluorine-containing Michael adducts have been synthesized in up to quantitative yield.