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Abstract <p>A series of methyl 2-benzyloxy-5-[2-(2-{[3-(substituted phenyl)-1-phenyl-1<i>H</i>-pyrazol-4-yl]­methylidene}hydrazinyl)-1,3-thiazol-4-yl]benzoates have been synthesized by one-pot condensation of methyl 2-benzyloxy-5-(2-bromoacetyl)benzoate, thiosemicarbazide, and 3-aryl-1-phenyl-1<i>H</i>-pyrazole-4-carbaldehydes under mild reaction condition. Various catalysts were used to optimize the synthesis conditions.</p>

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Efficient Multicomponent Synthesis of Methyl 2-(Benzyloxy)-5-[2-(2-{[3-(substituted phenyl)-1-phenyl-1H-pyrazol-4-yl]­methylidene}hydrazinyl)-1,3-thiazol-4-yl]benzoates

  • 期刊论文

  • 发表日期：

    2025年1月1日

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  • V. R. Bhosale,
  • V. S. Kapase

摘要

Abstract

A series of methyl 2-benzyloxy-5-[2-(2-{[3-(substituted phenyl)-1-phenyl-1H-pyrazol-4-yl]­methylidene}hydrazinyl)-1,3-thiazol-4-yl]benzoates have been synthesized by one-pot condensation of methyl 2-benzyloxy-5-(2-bromoacetyl)benzoate, thiosemicarbazide, and 3-aryl-1-phenyl-1H-pyrazole-4-carbaldehydes under mild reaction condition. Various catalysts were used to optimize the synthesis conditions.