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Abstract <p>One of the most extensively distributed elements in the Earth’s crust is aluminum sulfate Al<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub>, used in vaccinations, medications, and food additives. Vitamin C, a necessary nutrient, cannot be generated by humans due to the absence of a crucial enzyme in the biosynthesis route. Previous studies do not report enough data on the role of aluminum sulfate Al<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub> and vitamin C as companions, so the current study addressed this affair. The twenty rats were divided into 4 groups, five for each group: group 1―control, group 2―accompanied by Al<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub> at 0.1 mg/1, group 3―accompanied by Al<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub> at 0.2mg/L and group 4―Al<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub> at 0.2 mg/L plus vitamin C. For 21 days, the appropriate doses were given orally to rats. Histological analysis of the heart tissue revealed that a lack of effect of aluminum sulfate on inflammatory cells especially macrophages, meaning that vitamin C had an antagonistic effect on aluminum sulfate in when treated doses of Al (0.2 mg/L) with vitamin C<i>.</i></p>

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Effect Aluminum Sulfate on Cardiac Tissues and Possible Protective of Vitamin C in Male Rats

  • 期刊论文

  • 发表日期：

    2025年9月1日

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  • Eman Mohammed Hussain,
  • Hussein Kamil Awad,
  • Emam Atiyah Ibadi,
  • Sabrean Farhan Jawad

摘要

Abstract

One of the most extensively distributed elements in the Earth’s crust is aluminum sulfate Al2(SO4)3, used in vaccinations, medications, and food additives. Vitamin C, a necessary nutrient, cannot be generated by humans due to the absence of a crucial enzyme in the biosynthesis route. Previous studies do not report enough data on the role of aluminum sulfate Al2(SO4)3 and vitamin C as companions, so the current study addressed this affair. The twenty rats were divided into 4 groups, five for each group: group 1―control, group 2―accompanied by Al2(SO4)3 at 0.1 mg/1, group 3―accompanied by Al2(SO4)3 at 0.2mg/L and group 4―Al2(SO4)3 at 0.2 mg/L plus vitamin C. For 21 days, the appropriate doses were given orally to rats. Histological analysis of the heart tissue revealed that a lack of effect of aluminum sulfate on inflammatory cells especially macrophages, meaning that vitamin C had an antagonistic effect on aluminum sulfate in when treated doses of Al (0.2 mg/L) with vitamin C.