Abstract <p>This review presents the latest advances in drug therapy and diagnostics for various diseases, focusing on innovative approaches to address pressing challenges. It explores new methods of drug development and evaluates different delivery systems, including lipid-, polymer-, macrocycle- and metal-based carriers. Special attention is given to various routes of targeted drug delivery, as well as the possibility of delivering DNA and RNA. The review also addresses trends towards preferable use of natural components and personalized medicine. These trends reflect key developments in modern nanomedicine and other related fields.</p>

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Modern Strategies of Drug Therapy: Multi-Target Drug Delivery, Bioimaging, Diagnostics

  • O. V. Fedorova,
  • I. G. Ovchinnikova,
  • G. L. Rusinov,
  • V. V. Avdeeva,
  • A. P. Zhdanov,
  • K. Yu. Zhizhin,
  • N. T. Kuznetsov,
  • L. Ya. Zakharova,
  • D. A. Kuznetsova,
  • Yu. S. Razuvaeva,
  • E. P. Zhiltsova,
  • O. G. Sinyashin,
  • A. S. Alekseeva,
  • E. L. Vodovozova,
  • I. I. Abdrakhmanova,
  • A. Ibrahim,
  • V. V. Solovyeva,
  • A. V. Maltsev,
  • V. P. Fisenko,
  • S. O. Bachurin,
  • Yu. M. Mikhailov,
  • Yu. I. Aleksandrova,
  • D. N. Shurpik,
  • I. I. Stoikov,
  • A. Y. Ziganshina,
  • S. E. Solovieva,
  • I. S. Antipin,
  • M. A. Agafonov,
  • I. V. Terekhova,
  • P. M. Ilicheva,
  • P. S. Pidenko,
  • N. A. Burmistrova,
  • R. I. Moustafine,
  • V. R. Timergalieva,
  • Y. N. Zabolotnaya,
  • V. V. Khutoryanskiy,
  • A. M. Demin,
  • G. L. Levit,
  • V. N. Charushin,
  • V. P. Krasnov,
  • O. A. Goryacheva,
  • O. A. Mayorova,
  • S. M. Mesheryakova,
  • I. Yu. Goryacheva,
  • A. I. Ayupova,
  • А. А. Fattakhova,
  • А. А. Rizvanov,
  • O. A. Inozemtseva,
  • O. I. Gusliakova,
  • D. A. Gorin,
  • A. V. Gerasimov,
  • L. S. Zubaidullina,
  • M. A. Ziganshin,
  • S. V. Valiulin,
  • A. A. Onischuk,
  • A. N. Bezrukov,
  • Yu. G. Galyametdinov,
  • P. L. Padnya,
  • A. A. Nazarova,
  • E. D. Sultanova,
  • V. A. Burilov

摘要

Abstract

This review presents the latest advances in drug therapy and diagnostics for various diseases, focusing on innovative approaches to address pressing challenges. It explores new methods of drug development and evaluates different delivery systems, including lipid-, polymer-, macrocycle- and metal-based carriers. Special attention is given to various routes of targeted drug delivery, as well as the possibility of delivering DNA and RNA. The review also addresses trends towards preferable use of natural components and personalized medicine. These trends reflect key developments in modern nanomedicine and other related fields.