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Abstract <p>New nitrone-containing derivatives of pentacyclic triterpenoids were synthesized based on ursolic and betulonic acids. Their nitrone function is attached to the triterpenoid core at the C<sup>28</sup> position via a benzylamide spacer. The resulting nitrones are of interest as potentially biologically active compounds a wide range of pharmacological effects.</p>

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Synthesis of C28 Nitrones Based on Triterpenoids of the Lupane and Ursane Series

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月1日

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  • N. G. Komissarova,
  • A. V. Orlov,
  • L. V. Spirikhin

摘要

Abstract

New nitrone-containing derivatives of pentacyclic triterpenoids were synthesized based on ursolic and betulonic acids. Their nitrone function is attached to the triterpenoid core at the C28 position via a benzylamide spacer. The resulting nitrones are of interest as potentially biologically active compounds a wide range of pharmacological effects.