Abstract <p>A sustainable approach to synthesis of 4-aminoantipyrine based shiff bases by reaction between 4-aminoantipyrine and aldehydes has been developed by means of a single screw drill (SSD) as an alternative to conventional methods. The advantages of this method are the short time of the reaction, solvent-free conditions, low E-factor and high yield of the obtained products.</p>

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Sustainable Approach to 4-Aminoantipyrine Schiff Bases Using a Single Screw Drill Reactor

  • W. K. A. Al-Ithawi,
  • K. F. Al-Azawi,
  • A. M. Mohsen,
  • B. S. M. Al-Ghezi,
  • A. D. Sharapov,
  • D. S. Kopchuk,
  • I. S. Kovalev,
  • G. V. Zyryanov

摘要

Abstract

A sustainable approach to synthesis of 4-aminoantipyrine based shiff bases by reaction between 4-aminoantipyrine and aldehydes has been developed by means of a single screw drill (SSD) as an alternative to conventional methods. The advantages of this method are the short time of the reaction, solvent-free conditions, low E-factor and high yield of the obtained products.