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Abstract <p>The Biginelli products (dihydropyrimidines) and their derivatives are among the most abundant types of organic compounds. They are widely used in a wide range of therapeutic applications. In this work, the Biginelli reaction was carried out in the presence of sulfonated biochar derived from eucalyptus bark as an eco-freindly natural catalyst. The catalyst was characterized by XRD, FTIR and SEM/EDS techniques. The study also relates to the effects of some parameters on the yield and kinetics of the reaction, the effects of catalyst amount, temperature, catalyst regeneration and introduction order of reagents. High yields, short time, recyclability of the catalyst, simple product isolation are the noteworthy aspects of this protocol.</p>

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Sulfonated Biochar Derived from Eucalyptus Bark as Natural Catalyst in the Biginelli Reaction

  • 期刊论文

  • 发表日期：

    2025年3月27日

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  • K. Bouafina,
  • F. Belferdi,
  • F. Bouremmad

摘要

Abstract

The Biginelli products (dihydropyrimidines) and their derivatives are among the most abundant types of organic compounds. They are widely used in a wide range of therapeutic applications. In this work, the Biginelli reaction was carried out in the presence of sulfonated biochar derived from eucalyptus bark as an eco-freindly natural catalyst. The catalyst was characterized by XRD, FTIR and SEM/EDS techniques. The study also relates to the effects of some parameters on the yield and kinetics of the reaction, the effects of catalyst amount, temperature, catalyst regeneration and introduction order of reagents. High yields, short time, recyclability of the catalyst, simple product isolation are the noteworthy aspects of this protocol.