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Abstract <p>The article presents the design and investigation of a label-free biosensor based on a dielectrically modulated SiGe pocket based intrinsic channel Vertical Tunnel Field-Effect transistor (V-TFET). The proposed biosensor can detect different biomolecules such as protein, APTES (3-aminopropyltriethoxysilane), apomyoglobin, and gelatin. Different electrical metrics, such as drain current (<i>I</i><sub>D</sub>), electric field (<i>E</i><sub>f</sub>), threshold voltage (<i>V</i><sub>TH</sub>), electron band-to-band tunneling (eBTBT) rate, and drain current sensitivity (<i>S</i><sub>current</sub>), significantly changed while different biomolecules having different dielectric constants were incorporated. Additionally, both neutral, and charged biomolecules have been studied to determine the sensitivity of biosensor. A charged biomolecule is examined over a range of positive and negative charge densities with a&#xa0;dielectric constant of κ = 12. At κ = 12 (gelatin), the biosensor able to detect maximum ON-current of 4.90&#xa0;× 10<sup>–5</sup> A/µm and an OFF-current of 2.86 × 10<sup>–18</sup> A/µm with decent SS (12.494 mV/dec). Finally, both neutral and charged biomolecules have been studied to determine the biosensor’s sensitivity of κ = 12. The proposed biosensor obtained drain current and transconductance sensitivity readings of 3.90 × 10<sup>6</sup> and 8.46&#xa0;×&#xa0;10<sup>5</sup>, respectively. Lastly, the proposed biosensor device has been shown to produce notable improvement sensitivity and improved SS in comparison to other studies published.</p>

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Low-Power, High-Sensitivity Biosensor in Biomedical Diagnosis Incorporating SiGe-Pocket-P-I-N-V-TFET

  • 期刊论文

  • 发表日期：

    2026年3月13日

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  • Shankar Kumar Bharti,
  • Akhilesh Kumar,
  • Abhishek Kumar,
  • Ravi Pushkar,
  • Sourav Das

摘要

Abstract

The article presents the design and investigation of a label-free biosensor based on a dielectrically modulated SiGe pocket based intrinsic channel Vertical Tunnel Field-Effect transistor (V-TFET). The proposed biosensor can detect different biomolecules such as protein, APTES (3-aminopropyltriethoxysilane), apomyoglobin, and gelatin. Different electrical metrics, such as drain current (ID), electric field (Ef), threshold voltage (VTH), electron band-to-band tunneling (eBTBT) rate, and drain current sensitivity (Scurrent), significantly changed while different biomolecules having different dielectric constants were incorporated. Additionally, both neutral, and charged biomolecules have been studied to determine the sensitivity of biosensor. A charged biomolecule is examined over a range of positive and negative charge densities with a dielectric constant of κ = 12. At κ = 12 (gelatin), the biosensor able to detect maximum ON-current of 4.90 × 10–5 A/µm and an OFF-current of 2.86 × 10–18 A/µm with decent SS (12.494 mV/dec). Finally, both neutral and charged biomolecules have been studied to determine the biosensor’s sensitivity of κ = 12. The proposed biosensor obtained drain current and transconductance sensitivity readings of 3.90 × 106 and 8.46 × 105, respectively. Lastly, the proposed biosensor device has been shown to produce notable improvement sensitivity and improved SS in comparison to other studies published.