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Abstract <p>A review of publications on the development and improvement of methods for determining ricin and saxitoxin using various combinations and modifications of biochemical and immunospecific methods and also liquid chromatography–mass spectrometry is presented. Attention is focused on the importance of the choice of an analytical strategy and the optimization of sample preparation procedures and operation modes of analytical instruments. Published data on the selection of characteristic markers and methods for their determination are summarized.</p>

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Methods for Determining Saxitoxin and Ricin: A Review

  • 期刊论文

  • 发表日期：

    2025年12月15日

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  • I. I. Kovalenko,
  • A. V. Braun,
  • A. M. Grigoryev,
  • I. V. Rybalchenko,
  • V. N. Fateenkov

摘要

Abstract

A review of publications on the development and improvement of methods for determining ricin and saxitoxin using various combinations and modifications of biochemical and immunospecific methods and also liquid chromatography–mass spectrometry is presented. Attention is focused on the importance of the choice of an analytical strategy and the optimization of sample preparation procedures and operation modes of analytical instruments. Published data on the selection of characteristic markers and methods for their determination are summarized.