Scholarlink

Abstract <p>Magnetic hypercrosslinked polystyrene (<b>MHCPS</b>) is proposed for the group adsorption and preconcentration of quinolones. The conditions for magnetic solid-phase extraction are selected as follows: 25&#xa0;mL of solution (pH 6), sorbent mass 20 mg, and sorption time 20 min. The analytes have been desorbed with 2 mL of methanol. It is shown that the sorbent provides the quantitative extraction of all 23 studied compounds not only from aqueous solutions, but also from milk, bypassing the deproteinization stage. The determination is carried out by HPLC-tandem mass spectrometry using matrix calibration. The limits of detection and determination for quinolones are 0.012–0.12 and 0.04–0.4 μg/L, respectively, which are below their maximum residue levels in milk.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Preconcentration of Quinolones on Magnetic Hypercrosslinked Polystyrene before Their Determination by High-Performance Liquid Chromatography in Milk

  • 期刊论文

  • 发表日期：

    2025年8月19日

查看全文
  • Ya. A. Kulinich,
  • I. D. Puryskin,
  • V. V. Tolmacheva,
  • A. O. Melekhin,
  • V. V. Apyari,
  • S. G. Dmitrienko

摘要

Abstract

Magnetic hypercrosslinked polystyrene (MHCPS) is proposed for the group adsorption and preconcentration of quinolones. The conditions for magnetic solid-phase extraction are selected as follows: 25 mL of solution (pH 6), sorbent mass 20 mg, and sorption time 20 min. The analytes have been desorbed with 2 mL of methanol. It is shown that the sorbent provides the quantitative extraction of all 23 studied compounds not only from aqueous solutions, but also from milk, bypassing the deproteinization stage. The determination is carried out by HPLC-tandem mass spectrometry using matrix calibration. The limits of detection and determination for quinolones are 0.012–0.12 and 0.04–0.4 μg/L, respectively, which are below their maximum residue levels in milk.