Abstract <p>According to the conclusions of the UN Intergovernmental Panel on Climate Change, to determine the main causes of the global warming caused by an increase in the content of greenhouse gases in the atmosphere, an accurate assessment of their emissions and sinks is required. However, there are still significant uncertainties in the estimation of their budget. The present work studies the mesoscale inhomogeneities in the distribution of their fluxes and sinks based on hourly measurements at three air monitoring posts near Tomsk: TOR station, Fonovaya Observatory, and Basic Experimental Complex (BEC). This approach seems promising considering the significant role of soil in gas exchange processes. The differences in long-term (2013–2017) average concentrations between stations are shown to be within the ranges 116–195 μg/m³ for CO, 3.3–8.3 ppm for CO₂, 0.4–0.8 μg/m³ for NO, 4.6–15.5 μg/m³ for NO₂, 8.1–14.3 μg/m³ for O₃, and 2.3–6.9 μg/m³ for SO₂. Annual and daily variations in the concentration differences have been revealed for the first time. The results expand our knowledge about the dynamics of greenhouse and oxidizing gases in the atmosphere and can be useful in developing requirements for their measurement accuracy.</p>