Scholarlink

<p><b>Abstract</b>—It was found that, in Auliekol cattle, SNP <i>G</i>/<i>A</i> rs135173498 associated with live weight at birth (<i>p</i>‑value = 2.71E-06) is characterized by the absence of live-born calves homozygous for the rare genotype with a significant sample size of 497 animals. At the same time, calves with a heterozygous genotype were not characterized by a decrease in live weight at birth relative to the values of this indicator for the sample as a whole. The article analyzes possible mechanisms for the development of the phenotypic effect of SNP rs135173498 of the <i>NIPAL1</i> gene as a factor of embryonic lethality in Auliekol cattle, and, presumably, in the Kazakh Whiteheaded, Aberdeen Angus, and Charolais breeds.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Polymorphism of the NIPAL1 Gene rs135173498 as a Marker of Embryonic Lethality in Auliekol Cattle

  • 期刊论文

  • 发表日期：

    2025年1月1日

查看全文
  • A. V. Belaya,
  • E. A. Klimanova,
  • V. M. Norkina,
  • I. S. Beishova

摘要

Abstract—It was found that, in Auliekol cattle, SNP G/A rs135173498 associated with live weight at birth (p‑value = 2.71E-06) is characterized by the absence of live-born calves homozygous for the rare genotype with a significant sample size of 497 animals. At the same time, calves with a heterozygous genotype were not characterized by a decrease in live weight at birth relative to the values of this indicator for the sample as a whole. The article analyzes possible mechanisms for the development of the phenotypic effect of SNP rs135173498 of the NIPAL1 gene as a factor of embryonic lethality in Auliekol cattle, and, presumably, in the Kazakh Whiteheaded, Aberdeen Angus, and Charolais breeds.