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<b>Abstract</b>— <p>The paper presents the investigation results of an effect of thyroid hormone (triiodothyronine, Т<sub>3</sub>) on breathing frequency in zebrafish <i>Danio rerio</i> at rest. Fish exposure to a 10 ng/mL triiodothyronine solution for three days leads to a rise in the hormone level in their body approximately twofold and causes a significant increase in mean (opercular) ventilation frequency. Respiratory rhythm in <i>Danio</i> is characterized by alternation of periods of continuous and episodic breathing, which persist at exposure to T<sub>3</sub>. The article additionally discusses possible mechanisms of T<sub>3</sub>-induced increase in breathing frequency in fish.</p>

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An Effect of Triiodothyronine on Respiratory Rhythm in Zebrafish Danio rerio (Danionidae)

  • 期刊论文

  • 发表日期：

    2026年6月23日

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  • M. V. Nechaeva,
  • D. S. Pavlov

摘要

Abstract—

The paper presents the investigation results of an effect of thyroid hormone (triiodothyronine, Т3) on breathing frequency in zebrafish Danio rerio at rest. Fish exposure to a 10 ng/mL triiodothyronine solution for three days leads to a rise in the hormone level in their body approximately twofold and causes a significant increase in mean (opercular) ventilation frequency. Respiratory rhythm in Danio is characterized by alternation of periods of continuous and episodic breathing, which persist at exposure to T3. The article additionally discusses possible mechanisms of T3-induced increase in breathing frequency in fish.